Manchester Royal Eye Hospital, Oxford Road, Manchester M13 9WL, UK.
Br J Ophthalmol. 2012 Dec;96(12):1466-8. doi: 10.1136/bjophthalmol-2011-300996. Epub 2012 Mar 6.
Mucopolysaccharidoses (MPS) can cause corneal opacification that is currently difficult to objectively quantify. With newer treatments for MPS comes an increased need for a more objective, valid and reliable index of disease severity for clinical and research use. Clinical evaluation by slit lamp is very subjective and techniques based on colour photography are difficult to standardise. In this article the authors present evidence for the utility of dedicated image analysis algorithms applied to images obtained by a highly sophisticated iris recognition camera that is small, manoeuvrable and adapted to achieve rapid, reliable and standardised objective imaging in a wide variety of patients while minimising artefactual interference in image quality.
黏多糖贮积症（MPS）可导致角膜混浊，目前难以客观定量。随着 MPS 新疗法的出现，临床和研究用途需要一种更客观、有效和可靠的疾病严重程度指标。裂隙灯临床评估非常主观，基于彩色摄影的技术难以标准化。本文作者提出了证据，证明了专门的图像分析算法在通过高度复杂的虹膜识别相机获得的图像中的应用是有用的，该相机体积小、操作灵活，适用于在各种患者中实现快速、可靠和标准化的客观成像，同时最大限度地减少图像质量的人为干扰。
