Murayama K, Katsumi T, Watanabe K, Konishi K
Department of Urology, Kanazawa National Hospital.
Hinyokika Kiyo. 1990 Jun;36(6):697-700.
A case of primary malignant lymphoma of the bladder is presented. A 42-year-old woman was admitted to our clinic with the chief complaint of asymptomatic hematuria. Examination of cystoscopy, IVP, ultrasonography and CT scan suggested a non-epithelial tumor of the bladder, which was reported as malignant lymphoma, non-Hodgkin, by findings of transurethral biopsy. Subsequent systemic CT scan, Ga-scintigraphy and bone marrow puncture revealed no abnormalities. Therefore, this case was thought to be primary malignant lymphoma of the bladder. Partial cystectomy with pelvic lymph node resection was carried out. The tumor, 2 x 1 cm in diameter, invaded into the middle portion of muscularis. Histological diagnosis of the tumor was follicular lymphoma, medium-sized cell type according to LSG classification, and immunohistological findings also showed B-cell lymphoma. Resected lymph nodes had no signs of neoplasms. Postoperative adjuvant chemotherapy consisting of vincristine, cyclophosphamide and prednisolone was performed. She has been doing well without any clinical evidence of recurrence for 16 months after the operation.
本文报告一例原发性膀胱恶性淋巴瘤。一名42岁女性因无症状血尿为主诉入院。膀胱镜检查、静脉肾盂造影、超声检查及CT扫描显示膀胱非上皮性肿瘤，经尿道活检结果报告为非霍奇金恶性淋巴瘤。随后的全身CT扫描、镓闪烁扫描及骨髓穿刺均未发现异常。因此，该病例被认为是原发性膀胱恶性淋巴瘤。行膀胱部分切除术及盆腔淋巴结切除术。肿瘤直径2×1cm，侵犯至肌层中部。肿瘤组织学诊断为滤泡性淋巴瘤，根据LSG分类为中细胞型，免疫组织学检查结果也显示为B细胞淋巴瘤。切除的淋巴结无肿瘤迹象。术后进行了由长春新碱、环磷酰胺和泼尼松龙组成的辅助化疗。术后16个月，她情况良好，无任何复发的临床证据。
