Warshaw G A
University of Cincinnati College of Medicine, Ohio.
Am Fam Physician. 1990 Nov;42(5 Suppl):41S-47S.
Alzheimer's disease is the most common cause of progressive dementia in older adults. Diagnosis is based on a careful history, a thorough physical examination and appropriate laboratory studies. Although the pathology of Alzheimer's disease is well described, the etiology remains unknown. The only well-established risk factors are advanced age and family history. Management problems frequently include depression, delirium, wandering, urinary incontinence and iatrogenic disease.
阿尔茨海默病是老年人进行性痴呆最常见的病因。诊断基于详细的病史、全面的体格检查以及适当的实验室检查。尽管阿尔茨海默病的病理学已得到充分描述，但其病因仍不明。唯一已确定的风险因素是高龄和家族史。管理问题常常包括抑郁、谵妄、游走、尿失禁和医源性疾病。
