Nather Aziz, Keng Lin Wong, Aziz Zameer, Hj Ong Christine, Mc Feng Bernard, B Lin Clarabelle
Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Diabet Foot Ankle. 2011;2. doi: 10.3402/dfa.v2i0.6367. Epub 2011 Jun 16.
Our aim of this study was to compare the accuracy of three different modalities for testing sensory neuropathy in diabetic patients with and without diabetic foot problems. The three devices used included the pin-prick testing using the Neurotip® (PPT), the Semmes-Weinstein 5.07/10 g monofilament testing (SWMT), and the rapid-current perception threshold (R-CPT) measurements using the Neurometer® testing. Our study population consisted of 54 patients (108 feet) with diabetic foot problems treated at the National University Hospital in Singapore by our multi-disciplinary diabetic foot care team. Our results showed no difference in sensory neuropathy detected by PPT and 5.07/10 g SWMT in both the pathological and normal foot. In the pathological foot, there was significant increase in sensory neuropathy detected by the Neurometer® device at both the big toe and ankle sites as compared to PPT and 5.07/10 g SWMT. In the normal foot, there was a significant increase in sensory neuropathy detected by the Neurometer® device at the big toe site only as compared to PPT and 5.07/10 g SWMT. Finally, the Neurometer® measurements detected a statistically higher proportion of feet with sensory neuropathy as compared to detection by the PPT or 5.07/10 g SWMT.
本研究的目的是比较三种不同方法检测有或无糖尿病足问题的糖尿病患者感觉神经病变的准确性。所使用的三种设备包括使用Neurotip®进行针刺测试(PPT)、Semmes-Weinstein 5.07/10 g单丝测试(SWMT)以及使用Neurometer®测试进行的快速电流感觉阈值(R-CPT)测量。我们的研究对象包括54例(108只脚)有糖尿病足问题的患者,他们在新加坡国立大学医院由我们的多学科糖尿病足护理团队进行治疗。我们的结果显示,在病变足和正常足中,PPT和5.07/10 g SWMT检测到的感觉神经病变没有差异。在病变足中,与PPT和5.07/10 g SWMT相比,Neurometer®设备在大脚趾和脚踝部位检测到的感觉神经病变显著增加。在正常足中,与PPT和5.07/10 g SWMT相比,Neurometer®设备仅在大脚趾部位检测到的感觉神经病变显著增加。最后,与PPT或5.07/10 g SWMT检测相比,Neurometer®测量检测到感觉神经病变的足部比例在统计学上更高。