Winzenberg Tania, van der Mei Ingrid, Mason Rebecca S, Nowson Caryl, Jones Graeme
Menzies Research Institute Tasmania, University of Tasmania.
Aust Fam Physician. 2012 Mar;41(3):92-9.
The scientific literature related to vitamin D and bone health in older adults is extensive.
This article aims to summarise key practice points regarding vitamin D and bone health in older adults, relevant to general practitioners, and to provide an overview of the background literature to enable GPs to appreciate the extent of the supporting evidence.
Vitamin D supplementation can prevent falls, particularly in the vitamin D deficient elderly. However, adequate vitamin D levels and dietary calcium intake are needed for effective primary fracture prevention with greatest benefits occurring in the elderly with vitamin D deficiency and/or low dietary calcium intakes. For secondary fracture prevention, ie. preventing further fractures in the elderly who have already sustained a fragility fracture, specific anti-osteoporosis treatment is necessary. However, to maximise the benefits of these medications, vitamin D deficiency should be corrected and adequate dietary calcium consumed.
关于老年人维生素D与骨骼健康的科学文献极为丰富。
本文旨在总结与全科医生相关的、关于老年人维生素D与骨骼健康的关键实践要点，并概述背景文献，以使全科医生了解支持证据的范围。
补充维生素D可预防跌倒，尤其是在维生素D缺乏的老年人中。然而，有效的原发性骨折预防需要充足的维生素D水平和膳食钙摄入，在维生素D缺乏和/或膳食钙摄入量低的老年人中获益最大。对于继发性骨折预防，即预防已经发生脆性骨折的老年人再次骨折，需要进行特定的抗骨质疏松治疗。然而，为了使这些药物的益处最大化，应纠正维生素D缺乏并摄入充足的膳食钙。
