Pokupec Josipa Sanja Gruden, Gruden Zdenka, Gruden Vladimir
Zagreb Stomatological Polyclinic, Zagreb, Croatia.
Coll Antropol. 2011 Dec;35(4):1167-76.
Stomatopyrosis is commonly associated with stressful situations, which implies the importance of psychological conditions of the patients with this symptom. Patients suffering from burning mouth syndrome suffered from some psychical disturbances as well. The fact that depression and anxiety are closely connected with stomatopyrosis has been scientifically confirmed. The data which systematically led to this conclusion suggest the possibility of the existence of a psychogenic disturbance as an aetiological factor which leads to stomatopyrosis. Research which might be conducted in order to relate psychogenic disturbances with stomatopyrosis by means of various drugs and procedures, might provide an insight into the relatedness of these factors, which would enable us to treat the cause and not the consequence. This research has been directed towards establishing this "relatedness" by means of psychopharmatics and psychotherapy, and has been confirmed by means of psychological depression and anxiety tests. The research has been conducted on 120 respondents suffering from stomatopyrosis, who were also, as previously diagnosed, suffering from a psychical disturbance. The respondents were divided into 4 groups. Each group contained 30 respondents suffering from stomatopyrosis as the basic symptom, but with different psychogenic disturbances. These groups were: 1) antidepressants, 2) anxiolytics, 3) autogenic training and 4) control group. A detailed clinical and psychiatric check-up was conducted before the treatment started, and was repeated several times in different intervals: after a month, after two months and after four months. Respondents are still undergoing a therapy. Subjective assessment of the intensity of the burning sensation was obtained according to Visual analogue scale and two psychological questionnaires (depression test and anxiety test). Conclusion is: 1) Antidepressants and anxiolytic drugs have a prominent role in the treatment of stomatopyrosis. Psychological tests conducted after a four-month period have shown improvement--there was a decrease in anxiety--7.5%-8.8%, while depression has in some of the tested groups completely disappeared. At the same time, subjective evaluation of the intensity of the symptom has, according to VAS, showed a fall from 6.93-7.8 cm to 2.13-3.0 cm. At the beginning of the treatment, symptoms were described as "pretty often" with 36.7%-76.7% respondents, and as "permanent" with 23.3%-63.3% respondents. At the end of the treatment, the most frequent description regarding the frequency of the symptoms was "very rarely". 2) Autogenic training--psychotherapeutic anxiolytic technique--is the therapy of choice as far as stomatopyrosis is concerned, as it both eliminates the problems and emotionally rehabilitates the patient. 3) As far as the therapeutic progress is concerned, it can be taken as the "progress" of the time when the symptoms appear: during the treatment, the frequency and the duration of the symptoms have been shortened at night, while their occurrence during the day has been reported as relatively more frequent.
口腔灼痛症通常与压力状况相关,这表明有此症状患者的心理状况很重要。患有灼口综合征的患者也存在一些心理障碍。抑郁和焦虑与口腔灼痛症密切相关这一事实已得到科学证实。系统得出这一结论的数据表明,可能存在一种心理性障碍作为导致口腔灼痛症的病因。通过各种药物和程序来研究心理性障碍与口腔灼痛症之间关系的研究,可能会深入了解这些因素的相关性,从而使我们能够治疗病因而非仅仅治疗症状。这项研究旨在通过心理药理学和心理治疗来确定这种“相关性”,并通过心理抑郁和焦虑测试得到了证实。该研究针对120名患有口腔灼痛症且如先前诊断还患有心理障碍的受访者进行。受访者被分为4组。每组有30名以口腔灼痛症为基本症状但存在不同心理性障碍的受访者。这些组分别是:1)抗抑郁药组,2)抗焦虑药组,3)自生训练组和4)对照组。在治疗开始前进行了详细的临床和精神检查,并在不同间隔时间重复进行了几次:一个月后、两个月后和四个月后。受访者仍在接受治疗。根据视觉模拟量表以及两份心理问卷(抑郁测试和焦虑测试)获得了对灼痛感觉强度的主观评估。结论如下:1)抗抑郁药和抗焦虑药在口腔灼痛症的治疗中发挥着重要作用。四个月后进行的心理测试显示有改善——焦虑有所减轻——减轻了7.5% - 8.8%,而在一些测试组中抑郁完全消失。同时,根据视觉模拟量表,症状强度的主观评估显示从6.93 - 7.8厘米降至2.13 - 3.0厘米。治疗开始时,36.7% - 76.7%的受访者将症状描述为“相当频繁”,23.3% - 63.3%的受访者将其描述为“持续存在”。治疗结束时,关于症状频率最常见的描述是“非常罕见”。2)自生训练——一种心理治疗性抗焦虑技术——就口腔灼痛症而言是首选治疗方法,因为它既能消除问题又能使患者在情感上得到康复。3)就治疗进展而言,可以将其视为症状出现时间的“进展”:在治疗期间,症状在夜间出现的频率和持续时间缩短,而白天出现的频率相对更高。