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症状性癫痫中抗癫痫药物撤药的困境

Dilemma of antiepileptic drugs withdrawal in symptomatic epilepsy.

作者信息

Grahovac Dubravka Sepić, Bajek Goran, Vitezić Dinko, Mohar Lidija Tuskan, Ruzić Barsić Antonija, Grahovac Tanja, Bajek Snjezana

机构信息

University of Rijeka, School of Medicine, Rijeka, Croatia.

出版信息

Coll Antropol. 2011 Dec;35(4):1291-4.

PMID:22397274
Abstract

A successful treatment of epilepsy depends on numerous factors such as etiology, genetics and environmental impact. An exact diagnosis, treatment and an adequate selection of antiepileptic drugs (AED) are important from the very beginning. The patient with symptomatic epilepsy caused by the brain tumor (low-grade astrocytoma in the left parietal lobe, surgically removed 17 years after the first manifestation of illness) is presented in this study. He has been seizure free for 6 years. The represented case study deals with the risk-benefit analysis of the discontinuation of the prescribed antiepileptic treatment that has lasted for 23 years.

摘要

癫痫的成功治疗取决于众多因素,如病因、遗传学和环境影响。从一开始,准确的诊断、治疗以及抗癫痫药物(AED)的适当选择就很重要。本研究介绍了一名因脑肿瘤(左顶叶低度星形细胞瘤,在首次发病17年后手术切除)导致症状性癫痫的患者。他已经6年无癫痫发作。本案例研究涉及对持续了23年的抗癫痫治疗停药的风险效益分析。

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