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胃内球囊在全球肥胖治疗倡议中的地位。

Position of intragastric balloons in global initiative for obesity treatment.

作者信息

Nikolić Marko, Boban Marko, Ljubicić Neven, Supanc Vladimir, Mirosević Gorana, Nikolić Borka Pezo, Zjacić-Rotkvić Vanja, Gaćina Petar, Mirković Milan, Bekavac-Beslin Miroslav

机构信息

University of Zagreb, "Sestre Milosrdnice" University Hospital Center, Department of Internal Medicine, Zagreb, Croatia.

出版信息

Coll Antropol. 2011 Dec;35(4):1353-62.

Abstract

Obesity is chronic disease with multiple health consequences and among the most severe health problems worldwide. According to public health records around 65% of population in Croatia are overweight and 20% obese. National physicians chamber with support of Health and Social Welfare Ministry gave recommendations on diagnosing and treating of obesity in form of national consensus. Treatment of obesity is complex and enrolls multiple clinical specialties. Change of life style, strenuous physical activity and pharmacotherapy are part of conservative treatments. Patients are treated more efficiently by minimally invasive endoscopic procedures or bariatric surgery depending on starting body mass index score. Implantation of intragastric balloons is conceptually simple method of obesity treatment. Modern devices as Bio-Enterics intragastric balloons (BIB), (Inamed Health, USA) are gaining wide popularity among both patients and physicians. BIB intragastric offers the best gains with individuals ranging BMI from 35 to 40. Efficiency has relative timeline dependance from 85% at 6 months to 24% at 36 months. BIB offers substantial ameliorative influence on obesity comorbidities, particularly cardiovascular risk. Treatment with BIB is also efficient but transient treatment modality in morbidly and superobese individuals to reduce preoperative risks of general and bariatric surgery. Obesity treatment with BIB is well tolerated and safe, offering better quality of life. Nevertheless, due to relative poor results of conservative obesity treatments on long-term follow up further investigations defining new clinical parameters for solving treatment resistance. In order to provide resourcefully individualized approach modern perspectives are focused on endocrine constitutes of obesity. Hormonal effects of BIB treatment in compare to bariatric surgery are potentially interesting for the prospect studies.

摘要

肥胖是一种具有多种健康后果的慢性疾病,也是全球最严重的健康问题之一。根据公共卫生记录,克罗地亚约65%的人口超重,20%肥胖。在卫生和社会福利部的支持下,国家医师协会以国家共识的形式给出了肥胖诊断和治疗的建议。肥胖治疗很复杂,涉及多个临床专业。生活方式改变、剧烈体育活动和药物治疗是保守治疗的一部分。根据初始体重指数评分,通过微创内镜手术或减肥手术能更有效地治疗患者。胃内球囊植入是一种概念上简单的肥胖治疗方法。现代设备如Bio-Enterics胃内球囊(BIB,美国英诺美德医疗公司)在患者和医生中都越来越受欢迎。BIB胃内球囊在体重指数为35至40的个体中效果最佳。疗效有相对的时间依赖性,6个月时为85%,36个月时为24%。BIB对肥胖合并症有显著改善作用,尤其是心血管风险。BIB治疗也是治疗病态肥胖和超级肥胖个体以降低普通手术和减肥手术术前风险的有效但短暂的治疗方式。BIB治疗肥胖耐受性良好且安全,能提供更好的生活质量。然而,由于保守性肥胖治疗的长期随访结果相对较差,需要进一步研究以确定解决治疗抵抗的新临床参数。为了提供资源丰富的个性化方法,现代观点聚焦于肥胖的内分泌构成。与减肥手术相比,BIB治疗的激素效应可能是前瞻性研究的有趣课题。

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