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改善使用雌二醇和睾丸素植入物的绝经后妇女的血脂谱。

Improvement of the lipid profile in post menopausal women who use estradiol and testosterone implants.

机构信息

Department of Gynecology, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.

出版信息

Gynecol Endocrinol. 2012 Oct;28(10):767-9. doi: 10.3109/09513590.2012.664191. Epub 2012 Mar 8.

DOI:10.3109/09513590.2012.664191
PMID:22397585
Abstract

OBJECTIVE

This study evaluating the lipid profile in women in post menopause using the hormone therapy (HT) with implants of estradiol and testosterone.

METHOD

One year prospective cohort with 122 patients separated in group 1, not using HT, group 2 starting the use of HT, and group 3 with prior use of implants of estradiol and testosterone. All patients performed serum dosages of total cholesterol, HDL and triglycerides, in the beginning of the study and after 1 year.

DISCUSSION

The use of E and T implants showed some statistically significant decrease in TC at the beginning of the HT and some decrease in LDL in the group using HT. In the group without HT there was no difference in lipid profile.

摘要

目的

本研究评估了使用雌二醇和睾酮植入物进行激素治疗(HT)的绝经后妇女的血脂谱。

方法

对 122 名患者进行了为期 1 年的前瞻性队列研究,分为三组:第 1 组未使用 HT,第 2 组开始使用 HT,第 3 组之前使用过雌二醇和睾酮植入物。所有患者在研究开始时和 1 年后均进行了血清总胆固醇、HDL 和甘油三酯的检测。

讨论

雌二醇和睾酮植入物的使用在 HT 开始时显示 TC 有一定的统计学显著降低,且在使用 HT 的组中 LDL 也有一定程度的降低。在未使用 HT 的组中,血脂谱没有差异。

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