Centre for Medicine and Oral Health, Griffith Health Institute, Griffith University Gold Coast Campus, Gold Coast, QLD 4222, Australia.
J Infect Chemother. 2012 Dec;18(6):955-7. doi: 10.1007/s10156-012-0400-0. Epub 2012 Mar 8.
Herpes zoster (HZ) is a clinical manifestation of the reactivation of the varicella zoster virus (VZV). HZ of the male genital area is a rarely reported condition. The exact mechanism of latency and reactivation of VZV in these patients is unknown. The incidence of HZ can be associated with various conditions such as malignancies, immune deficiencies, autoimmune diseases, psychological conditions, and human immunodeficiency infection or HIV disease. In this report, we describe a rare case of HZ on male genitalia following the administration of immunosuppressant drugs for bowel cancer. The patient developed classical features of HZ during chemotherapy, 2 years after the initial chemotherapy for his bowel cancer. The ulcers of HZ lesions were treated with chlorhexidine (Curasept) ointment to prevent secondary bacterial infection. All the lesions subsided gradually and in 2 weeks with no later symptoms or pain. Genitalia are an unusual site of eruption in HZ. Patients with malignancy and iatrogenic immunodeficiency have an increased risk of reactivation of VZV and development of HZ.
带状疱疹（HZ）是水痘带状疱疹病毒（VZV）再激活的临床表现。男性生殖器区域的 HZ 是一种罕见的报道情况。这些患者中 VZV 潜伏和再激活的确切机制尚不清楚。HZ 的发病率可能与多种情况相关，如恶性肿瘤、免疫缺陷、自身免疫性疾病、心理状况以及人类免疫缺陷感染或 HIV 疾病。在本报告中，我们描述了一例罕见的男性生殖器 HZ 病例，该病例发生在接受免疫抑制药物治疗肠癌之后。该患者在肠癌初始化疗 2 年后，于化疗期间出现典型的 HZ 特征。HZ 病变的溃疡用洗必泰（Curasept）软膏治疗，以防止继发细菌感染。所有病变逐渐消退，2 周后无进一步症状或疼痛。生殖器是 HZ 皮疹的不常见部位。患有恶性肿瘤和医源性免疫缺陷的患者 VZV 再激活和 HZ 发展的风险增加。
