Road to the chromosome 9p-linked ALS/FTD locus.
作者信息
Traynor Bryan J
机构信息
Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD 20892, USA.
出版信息
J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):356-7. doi: 10.1136/jnnp-2012-302429.
Abstract
摘要
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本文引用的文献
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.C9ORF72 上的六核苷酸重复扩展是 9p21 连锁 ALS-FTD 的原因。
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2
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.非编码区 C9ORF72 内的 GGGGCC 六核苷酸重复扩展导致 9 号染色体连锁额颞叶痴呆和肌萎缩侧索硬化症。
Neuron. 2011 Oct 20;72(2):245-56. doi: 10.1016/j.neuron.2011.09.011. Epub 2011 Sep 21.
3
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.芬兰肌萎缩侧索硬化症中 9p21 染色体：一项全基因组关联研究。
Lancet Neurol. 2010 Oct;9(10):978-85. doi: 10.1016/S1474-4422(10)70184-8.
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Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.在英国和其他七个国家的散发型肌萎缩侧索硬化症中染色体 9p21：一项全基因组关联研究。
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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.7p21 常见变异与含有 TDP-43 包涵体的额颞叶变性有关。
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Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.全基因组关联研究确定19p13.3（UNC13A）和9p21.2为散发性肌萎缩侧索硬化症的易感基因座。
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Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3.伴有额颞叶痴呆的家族性肌萎缩侧索硬化症与9号染色体p13.2 - 21.3区域的一个基因座相关。
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