Bronz G, Dubach H U, Geroulanos S, Jadoul D, Urfer K, Wüst W, Senning A
Helv Chir Acta. 1979 May;46(1-2):141-52.
15 cases of bronchiolo-alveolar cell carcinoma were observed at the Dept. of Surgery of the University Hospital of Zurich from 1961 to 1976. The mean age of these patients was 56 years. The sex distribution was 13 males and 2 females. Five cases were discovered accidentally; the symptoms of the remaining 10 were uncharacteristic. Cytology, bronchoscopy and mediastinoscopy were negative at early stages. Diagnosis was made by histologic examination of the specimens only. Needle biopsy, performed routinely over recent years, proved helpful in 4 cases. In 12 out of 14 patients, lobectomy was considered 'radical'; nevertheless, only 2 survived more than 5 years. The disseminated form of the bronchiolo-alveolar cell carcinoma is characterized by a particularly poor prognosis. According to our experience and to the literature, only the solitary, nodular type shows a more favourable outlook.
1961年至1976年间，苏黎世大学医院外科观察了15例细支气管肺泡癌患者。这些患者的平均年龄为56岁。性别分布为13名男性和2名女性。5例为偶然发现；其余10例症状不典型。早期细胞学、支气管镜检查和纵隔镜检查均为阴性。仅通过标本的组织学检查做出诊断。近年来常规进行的针吸活检在4例中证明有帮助。14例患者中有12例接受了肺叶切除术，被认为是“根治性”的；然而，只有2例存活超过5年。细支气管肺泡癌的弥漫型预后特别差。根据我们的经验和文献，只有孤立结节型预后较好。
