Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
Radiother Oncol. 2012 May;103(2):151-4. doi: 10.1016/j.radonc.2012.01.008. Epub 2012 Mar 6.
Even though tumor progression under neoadjuvant chemotherapy is uncommon, its locoregional management remains absolutely unclear. What is the best time for radical surgery or radiotherapy? "Rescue" chemo-radiotherapy could be a suitable radiosensitizing strategy to further reduce tumor progression and allow curative surgery while maintaining systemic therapy.
尽管新辅助化疗下肿瘤进展并不常见,但局部区域管理仍完全不清楚。根治性手术或放疗的最佳时机是什么?“挽救性”放化疗可能是一种合适的增敏策略,可进一步降低肿瘤进展的风险,允许进行治愈性手术,同时保持全身治疗。