Moskalewski Stanisław, Jankowska-Steifer Ewa
Department and Division of Histology and Embryology, Medical University of Warsaw.
Ortop Traumatol Rehabil. 2012 Jan-Feb;14(1):13-21. doi: 10.5604/15093492.976894.
A very low coefficient of friction in joints makes it difficult to define clearly the mechanism of cartilage lubrication. The present paper describes the two currently predominant and mutually complementary views aiming to elucidate this mechanism. The first mechanism, referred to as hydrostatic lubrication, involves interstitial fluid pressurization from the cartilage and its importance for the formation of a layer separating the weight-bearing surfaces. The second mechanism, called boundary lubrication, assumes the existence of a substance that binds to the cartilage surface, permanently separating the friction elements. It has not been clearly determined which substances occurring in the synovial fluid function as boundary lubricants. The authors briefly describe the physicochemical properties of lubricin, surface-active phospholipids and hyaluronic acid, including their role in boundary lubrication.
关节中极低的摩擦系数使得难以清晰界定软骨润滑的机制。本文描述了目前两种主要且相互补充的观点，旨在阐明这一机制。第一种机制，称为流体静压润滑，涉及软骨间液的增压及其对形成分隔承重表面的一层物质的重要性。第二种机制，称为边界润滑，假定存在一种与软骨表面结合的物质，永久性地分隔摩擦元件。目前尚未明确确定滑液中哪些物质起到边界润滑剂的作用。作者简要描述了润滑素、表面活性磷脂和透明质酸的物理化学性质，包括它们在边界润滑中的作用。
