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Bilateral subdural hemorrhage as a serious adverse event of dasatinib in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.

作者信息

Yhim Ho-Young, Kim Hee Sun, Lee Na-Ri, Song Eun-Kee, Kwak Jae-Yong, Yim Chang-Yeol

出版信息

Int J Hematol. 2012 May;95(5):585-7. doi: 10.1007/s12185-012-1045-6. Epub 2012 Mar 9.

DOI:10.1007/s12185-012-1045-6
PMID:22403059
Abstract
摘要

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1
Bilateral subdural hemorrhage as a serious adverse event of dasatinib in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Int J Hematol. 2012 May;95(5):585-7. doi: 10.1007/s12185-012-1045-6. Epub 2012 Mar 9.
2
Dasatinib: a tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia and philadelphia chromosome-positive acute lymphoblastic leukemia.达沙替尼：一种用于治疗慢性粒细胞白血病和费城染色体阳性急性淋巴细胞白血病的酪氨酸激酶抑制剂。
Clin Ther. 2007 Nov;29(11):2289-308. doi: 10.1016/j.clinthera.2007.11.005.
3
Use of dasatinib in the patient with Philadelphia chromosome-positive acute lymphoblastic leukaemia with resistance to imatinib and renal failure.达沙替尼在对伊马替尼耐药且伴有肾衰竭的费城染色体阳性急性淋巴细胞白血病患者中的应用。
J Clin Pharm Ther. 2008 Jun;33(3):329-30. doi: 10.1111/j.1365-2710.2008.00916.x.
4
Rapid-onset pulmonary arterial hypertension in a patient with acute lymphoblastic leukemia treated with dasatinib.一名接受达沙替尼治疗的急性淋巴细胞白血病患者出现快速进展的肺动脉高压。
Herz. 2013 Dec;38(8):931-3. doi: 10.1007/s00059-013-3765-7. Epub 2013 Feb 23.
5
Spontaneous subdural hematoma in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia with normal platelet count after dasatinib treatment.达沙替尼治疗后血小板计数正常的费城染色体阳性急性淋巴细胞白血病患者发生自发性硬膜下血肿。
Platelets. 2015;26(5):491-4. doi: 10.3109/09537104.2014.935316. Epub 2014 Jul 15.
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Severe hemorrhagic colitis caused by dasatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia.
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Clin Adv Hematol Oncol. 2010 Feb;8(2):128-32.
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Dasatinib-induced gastric antral vascular ectasia in a patient with acute lymphoblastic leukaemia.
Br J Haematol. 2015 Jun;169(5):612. doi: 10.1111/bjh.13407. Epub 2015 Apr 8.
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Dasatinib dosing strategies in Philadelphia chromosome-positive leukemia.达沙替尼在费城染色体阳性白血病中的给药策略。
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Dasatinib-induced complete molecular response after allogeneic hematopoietic stem cell transplantation in Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to prior imatinib-containing regimen: a case report and discussion.达沙替尼诱导费城染色体阳性急性淋巴细胞白血病对既往含伊马替尼方案耐药患者异基因造血干细胞移植后完全分子缓解：1 例病例报告并讨论
Med Oncol. 2010 Dec;27(4):1123-6. doi: 10.1007/s12032-009-9347-0. Epub 2009 Nov 3.

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Middle meningeal artery embolization for symptomatic chronic subdural hematoma in the setting of severe transfusion-refractory thrombocytopenia: A case study and review of literature.严重输血难治性血小板减少症患者症状性慢性硬膜下血肿的脑膜中动脉栓塞术：病例报告及文献综述
Surg Neurol Int. 2023 Jun 30;14:223. doi: 10.25259/SNI_1051_2022. eCollection 2023.
2
Recurrent Gastrointestinal Hemorrhage in Children with Philadelphia-Positive B-Cell Acute Lymphoblastic Leukemia Treated with Dasatinib: Case Reports.达沙替尼治疗费城染色体阳性B细胞急性淋巴细胞白血病儿童复发性胃肠道出血：病例报告
Case Rep Hematol. 2020 Feb 10;2020:5678210. doi: 10.1155/2020/5678210. eCollection 2020.

本文引用的文献

1
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia.达沙替尼与伊马替尼治疗新诊断的慢性期慢性髓性白血病。
N Engl J Med. 2010 Jun 17;362(24):2260-70. doi: 10.1056/NEJMoa1002315. Epub 2010 Jun 5.
2
The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo.新型酪氨酸激酶抑制剂及抗癌药物达沙替尼在体外和体内均可可逆地影响血小板活化。
Blood. 2009 Aug 27;114(9):1884-92. doi: 10.1182/blood-2009-02-205328. Epub 2009 Jun 3.
3
Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia.
酪氨酸激酶抑制剂诱发慢性髓性白血病患者的血小板功能障碍。
Blood. 2009 Jul 9;114(2):261-3. doi: 10.1182/blood-2008-09-180604. Epub 2009 May 4.
4
Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up.达沙替尼140毫克每日一次与70毫克每日两次用于对伊马替尼耐药或不耐受的加速期慢性髓性白血病患者的3期研究：15个月中位随访
Blood. 2009 Jun 18;113(25):6322-9. doi: 10.1182/blood-2008-11-186817. Epub 2009 Apr 15.
5
Bleeding diathesis in patients with chronic myelogenous leukemia receiving dasatinib therapy.接受达沙替尼治疗的慢性粒细胞白血病患者的出血素质
Cancer. 2009 Jun 1;115(11):2482-90. doi: 10.1002/cncr.24257.
6
Metabolism and disposition of dasatinib after oral administration to humans.达沙替尼口服给药后在人体内的代谢与处置。
Drug Metab Dispos. 2008 Jul;36(7):1357-64. doi: 10.1124/dmd.107.018267. Epub 2008 Apr 17.
7
Sprycel for chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to or intolerant of imatinib mesylate.施达赛用于治疗对甲磺酸伊马替尼耐药或不耐受的慢性髓性白血病和费城染色体阳性的急性淋巴细胞白血病。
Clin Cancer Res. 2008 Jan 15;14(2):352-9. doi: 10.1158/1078-0432.CCR-07-4175.
8
Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study.达沙替尼可使对伊马替尼耐药或不耐受的费城染色体阳性成人急性淋巴细胞白血病患者迅速获得血液学和细胞遗传学缓解：一项2期研究的中期结果。
Blood. 2007 Oct 1;110(7):2309-15. doi: 10.1182/blood-2007-02-073528. Epub 2007 May 11.
9
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: a randomized phase 2 trial.达沙替尼或高剂量伊马替尼用于一线伊马替尼治疗失败后的慢性期慢性髓性白血病：一项随机2期试验。
Blood. 2007 Jun 15;109(12):5143-50. doi: 10.1182/blood-2006-11-056028. Epub 2007 Feb 22.
10
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias.达沙替尼用于伊马替尼耐药的费城染色体阳性白血病。
N Engl J Med. 2006 Jun 15;354(24):2531-41. doi: 10.1056/NEJMoa055229.