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理解药物滥用与依赖的神经生物学、评估及治疗:重症护理护士指南

Understanding the neurobiology, assessment, and treatment of substances of abuse and dependence: a guide for the critical care nurse.

作者信息

Genung Vanessa

机构信息

Wilson School of Nursing, Midwestern State University, Wichita Falls, TX 76308, USA.

出版信息

Crit Care Nurs Clin North Am. 2012 Mar;24(1):117-30. doi: 10.1016/j.ccell.2012.01.007.

Abstract

What do I as a critical care nurse do? Nurses, by virtue of being trained in health promotion, and also because they interact with patients, families, and communities, have firsthand opportunities to play an active role in practicing primary prevention. To avoid the first occurrence of substance abuse, assess community need, assess facility needs, and identify potential risk. Identify the magnitude of the problem. Intervene early with the youth and at-risk populations. Refer patients and their families to mental health specialists. Provide education to patients, families, communities. To reduce occurrences of substance abuse, practicing secondary prevention requires prompt action in the earliest moments of recognizing a problem and directing patients to early intervention and rehabilitation. Screening your patients, providing brief education, and prompt referral constitutes early intervention. To retard the progress of the disease, practice tertiary prevention by providing education, counseling, and support to the afflicted in achieving and maintaining sobriety through medication compliance and rehabilitative group and counseling work. The goal of intervention in the lives of substance abusers is to stop drug use, avoid relapse, and sustain recovery. After years of research, NIDA has identified 13 fundamental principles to effective drug abuse treatment. 1. Addiction is a complex but treatable disease that affects brain function and behavior. 2. No single treatment is appropriate for everyone. 3. Treatment needs to be readily available. 4. Effective treatment attends to multiple needs of the individual, not just his or her drug abuse. 5. Remaining in treatment for an adequate period of time is critical. 6. Counseling--individual and/or group--and other behavioral therapies are the most commonly used forms of drug abuse treatment. 7. Medications are an important element of treatment for many patients, especially when combined with counseling and other behavioral therapies. 8. An individual's treatment and services plan must be assessed continually and modified as necessary to ensure it meets his or her changing needs. 9. Many drug-addicted individuals also have other mental disorders that need treatment. 10. Medically assisted detoxification in the first stage of addiction treatment and by itself does little to change long-term drug abuse. 11. Treatment does not need to be voluntary to be effective. 12. Drug use during treatment must be monitored continuously, because lapses during treatment do occur. 13. Treatment programs should assess patients for the presence of HIV/AIDS, hepatitis B and C, tuberculosis, and other infectious diseases, as well as provide targeted risk-reduction counseling to help patients modify or change behaviors that place them at risk of contracting or spreading infectious diseases. To truly impact this disease, there needs to be improvement in the identification of risk factors and early identification and early intervention with children and adolescents. The future of neuroscience is in objective brain scans and genetic testing. Out of these approaches can come more objective measures of addiction and dependence using brain scans and genetic testing. These measures would potentially allow for the development of vaccines for specific drugs of abuse and dependence, as well as increasingly selective and effective pharmacologic approaches for treatment and a new consensus on standard of care for substance dependence.

摘要

作为一名重症监护护士,我要做些什么呢?护士凭借在健康促进方面接受的培训,以及与患者、家庭和社区的互动,拥有在实践一级预防中发挥积极作用的第一手机会。为避免药物滥用首次发生,需评估社区需求、评估机构需求并识别潜在风险。确定问题的严重程度。尽早对青少年和高危人群进行干预。将患者及其家属转介给心理健康专家。为患者、家庭和社区提供教育。为减少药物滥用的发生,实施二级预防需要在最早识别问题时迅速采取行动,并引导患者进行早期干预和康复。对患者进行筛查、提供简短教育并及时转介构成早期干预。为延缓疾病进展,实施三级预防,通过提供教育、咨询和支持,帮助患者通过药物依从性以及康复小组和咨询工作实现并保持清醒。对药物滥用者生活进行干预的目标是停止药物使用、避免复发并维持康复状态。经过多年研究,美国国家药物滥用研究所确定了有效药物滥用治疗的13项基本原则。1. 成瘾是一种复杂但可治疗的疾病,会影响大脑功能和行为。2. 没有一种单一的治疗方法适用于所有人。3. 治疗需要随时可得。4. 有效的治疗要关注个体的多种需求,而不仅仅是其药物滥用问题。5. 在足够长的时间内接受治疗至关重要。6. 个体和/或团体咨询以及其他行为疗法是最常用的药物滥用治疗形式。7. 药物对许多患者来说是治疗的重要组成部分,尤其是与咨询和其他行为疗法相结合时。8. 必须持续评估个人的治疗和服务计划,并根据需要进行修改,以确保其满足个人不断变化的需求。9. 许多药物成瘾者还患有其他需要治疗的精神障碍。10. 在成瘾治疗的第一阶段,医学辅助排毒本身对改变长期药物滥用作用不大。11. 治疗不一定需要自愿才有效。12. 治疗期间必须持续监测药物使用情况,因为治疗期间确实会出现复发情况。13. 治疗项目应评估患者是否感染艾滋病毒/艾滋病、乙型和丙型肝炎、结核病及其他传染病,并提供有针对性的降低风险咨询,以帮助患者改变或调整使其有感染或传播传染病风险的行为。为真正影响这种疾病,需要在识别风险因素以及对儿童和青少年进行早期识别和早期干预方面有所改进。神经科学的未来在于客观的脑部扫描和基因检测。通过这些方法,可以利用脑部扫描和基因检测得出更客观的成瘾和依赖测量方法。这些测量方法可能会促成针对特定滥用和依赖药物的疫苗研发,以及越来越有选择性和有效性的药物治疗方法,还会形成关于药物依赖护理标准的新共识。

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