San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
J Subst Abuse Treat. 2012 Oct;43(3):291-302. doi: 10.1016/j.jsat.2011.12.010. Epub 2012 Mar 8.
This study examined the longitudinal association between substance use and depressive symptoms in veterans receiving outpatient treatment for comorbid substance use disorder and major depression. Veterans (N = 237, mean age = 48.2 years, 90% male, 70% Caucasian) received either 6 months of group integrated cognitive-behavioral therapy or twelve-step facilitation. Hamilton Depression Rating Scale scores and percent days using any substance were assessed every 3 months up to 1 year posttreatment. Greater substance use predicted time-varying elevations in depression above individual patterns of change in depression. Moreover, change in depressive symptoms was associated with change in both the likelihood of any substance use and the frequency of use during the treatment and follow-up periods. Changes in these symptoms appear to be linked, such that individuals with greater reductions in substance use have greater reductions in depressive symptoms (and vice versa).
这项研究调查了在接受门诊治疗共病物质使用障碍和重度抑郁症的退伍军人中，物质使用与抑郁症状之间的纵向关联。退伍军人（N=237，平均年龄 48.2 岁，90%为男性，70%为白种人）接受了 6 个月的团体综合认知行为疗法或十二步促进治疗。在治疗后 1 年内，每 3 个月评估一次汉密尔顿抑郁评定量表评分和任何物质的使用天数。更多的物质使用预示着抑郁的时间变化高于抑郁变化的个体模式。此外，抑郁症状的变化与治疗和随访期间任何物质使用的可能性以及使用频率的变化都有关系。这些症状的变化似乎是相互关联的，即物质使用减少较多的个体抑郁症状也会有更大的减少（反之亦然）。
