Department of Pathology, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Trivandrum, Kerala, India.
Neurol India. 2012 Jan-Feb;60(1):96-9. doi: 10.4103/0028-3886.93614.
Embryonal tumor with multilayered rosettes (ETMR) is a well-recognized histopathological variant of primitive neurectodermal tumors of the central nervous system. This tumor depicts histopathological features that are common to both ependymoblastoma (EBL) and neuroblastoma. Here we report two pediatric cases of ETMR, one exhibiting dominant neuronal differentiation and the other with dominant glial differentiation, thereby expanding the previously known pathologic spectrum. The varying histological features, common morphologic diagnostic difficulties as well as variable postsurgical survival of this entity compared to similar embryonal tumors are highlighted.
胚胎性肿瘤伴多层菊形团（ETMR）是中枢神经系统原始神经外胚层肿瘤的一种公认的组织病理学变异型。该肿瘤具有与室管膜母细胞瘤（EBL）和神经母细胞瘤均相同的组织病理学特征。在此，我们报告了两例儿童 ETMR 病例，其中一例表现出明显的神经元分化，另一例则以神经胶质分化为主，从而扩展了之前已知的病理谱。本文强调了该肿瘤的各种组织学特征、常见的形态学诊断困难以及与类似胚胎性肿瘤相比手术后的生存情况存在差异。
