Emory Transplant Center, Emory University, Atlanta, GA 30322, USA.
Transplantation. 2012 Jun 15;93(11):1086-7. doi: 10.1097/TP.0b013e31824b073f.
To date, there are more than 80 reports of vascularized composite allografts (VCAs; a.k.a. composite tissue allotransplantation). However, the classification of this type of transplantation for oversight purposes has not been clarified. From a biological and regulatory perspective, we propose that VCA retrieval and transplantation is akin to organ transplantation and should be incorporated into the organ oversight structure. As VCA becomes more of a clinical reality, the need for a methodical approach to allocation and access to more donors will develop. Such an allocation system will likely incorporate parameters that deviate from those used for organ transplantation. To develop an effective and balanced system, the use of existing regulatory agencies that oversee solid organs should provide the maximum benefit to the patients and the society.
迄今为止，已有超过 80 份关于血管化复合移植物（VCA；也称为复合组织同种异体移植）的报告。然而，为了监督目的，这种移植类型的分类尚未明确。从生物学和监管的角度来看，我们提出 VCA 的检索和移植类似于器官移植，应纳入器官监督结构。随着 VCA 越来越成为临床现实，对分配方法和更多供体的获取的需求将会发展。这样的分配系统可能会纳入与器官移植使用的参数不同的参数。为了开发一个有效和平衡的系统，利用现有的监管实体器官的监管机构应该为患者和社会提供最大的利益。
