Shneider Benjamin L, Bosch Jaime, de Franchis Roberto, Emre Sukru H, Groszmann Roberto J, Ling Simon C, Lorenz Jonathan M, Squires Robert H, Superina Riccardo A, Thompson Ann E, Mazariegos George V
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.
Pediatr Transplant. 2012 Aug;16(5):426-37. doi: 10.1111/j.1399-3046.2012.01652.x. Epub 2012 Mar 13.
Complications of portal hypertension in children lead to significant morbidity and are a leading indication for consideration of liver transplantation. Approaches to the management of sequelae of portal hypertension are well described for adults and evidence-based approaches have been summarized in numerous meta-analyses and conferences. In contrast, there is a paucity of data to guide the management of complications of portal hypertension in children. An international panel of experts was convened on April 8, 2011 at The Children's Hospital of Pittsburgh of UPMC to review and adapt the recent report of the Baveno V Consensus Workshop on the Methodology of Diagnosis and Therapy in Portal Hypertension to the care of children. The opinions of that expert panel are reported.
儿童门静脉高压症的并发症会导致严重发病,是考虑肝移植的主要指征。成人门静脉高压后遗症的管理方法已有详尽描述,众多荟萃分析和会议也总结了循证方法。相比之下,指导儿童门静脉高压并发症管理的数据却很匮乏。2011年4月8日,一个国际专家小组在匹兹堡大学医学中心儿童医院召开会议,对巴韦诺V门静脉高压诊断与治疗方法共识研讨会的最新报告进行审查,并使其适用于儿童护理。现将该专家小组的意见报告如下。