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松弛皮肤型蕈样肉芽肿。

Cutis laxa-like mycosis fungoides.

机构信息

Department of Dermatology, Hospital del Mar, Barcelona, Spain.

出版信息

J Dermatol. 2012 Jun;39(6):548-51. doi: 10.1111/j.1346-8138.2012.01523.x. Epub 2012 Mar 13.

Abstract

Mycosis fungoides is the most common form of primary cutaneous T-cell lymphoma. Several clinical and clinicopathological variants of mycosis fungoides have been reported. A 75-year-old woman presenting with multiple ill-defined areas of marked cutaneous wrinkling on the trunk and extremities is reported. Histopathological examination showed characteristic features of mycosis fungoides along with an interstitial dermal infiltrate composed predominantly of atypical lymphocytes with histiocytes intermingled within the collagen bundles. A focal reduction and fragmentation of elastic fibers was demonstrated. This observation illustrates a peculiar and previously unreported clinicopathological presentation of mycosis fungoides: cutis laxa-like mycosis fungoides, expanding the spectrum of mycosis fungoides variants associated with abnormalities of the dermal elastic fibers.

摘要

蕈样肉芽肿是原发性皮肤 T 细胞淋巴瘤最常见的形式。已经报道了几种蕈样肉芽肿的临床和临床病理变异型。报告了一名 75 岁女性,其躯干和四肢出现多个界限不清的明显皮肤皱折区域。组织病理学检查显示蕈样肉芽肿的特征性特征,以及间质真皮浸润,主要由不典型淋巴细胞组成,其间混有组织细胞,在胶原束内。弹性纤维的局部减少和断裂。这一观察结果说明了蕈样肉芽肿的一种特殊且以前未报道的临床病理表现:松弛皮肤样蕈样肉芽肿,扩大了与真皮弹性纤维异常相关的蕈样肉芽肿变异型的范围。

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