Gupta Kirti, Das Ashim, Menon Prema, Kakkar Nandita, Rao K L N, Joshi Kusum
Post-Graduate Institute of Medical Education and Research, Department of Histopathology, Chandigarh, India.
Fetal Pediatr Pathol. 2012 Apr;31(2):74-86. doi: 10.3109/15513815.2011.650287.
A retrospective analysis of lobectomy, pneumonectomy, cystectomy specimens (10 years) and stillbirth/neonatal autopsies (5 years) was carried out to analyze the histologic spectrum of congenital pulmonary developmental disorders/malformations. The autopsy data was analyzed to identify the lesions that are more diffuse and not amenable to surgical management. A total of 166 cases of pulmonary developmental disorders/ malformation were found. Out of 2,155 stillbirth/neonatal autopsies, there were 105 cases of pulmonary hypoplasia, 2 cases of congenital pulmonary lymphangiectasis, 2 cases of extralobar sequestration, and 3 cases of congenital pulmonary airway malformation (CPAM). Among the surgical specimens, there were 21 cases of CPAM, 11 cases of intralobar sequestration, 5 cases of congenital lobar emphysema and 17 cases of bronchogenic cyst. All these malformations have been described in reference to the latest updated classification of developmental disorders/malformations.
对肺叶切除术、全肺切除术、膀胱切除术标本（10年）以及死产/新生儿尸检（5年）进行回顾性分析，以分析先天性肺发育障碍/畸形的组织学谱。对尸检数据进行分析，以确定那些更弥漫且不适合手术治疗的病变。共发现166例肺发育障碍/畸形。在2155例死产/新生儿尸检中，有105例肺发育不全、2例先天性肺淋巴管扩张症、2例肺叶外隔离症和3例先天性肺气道畸形（CPAM）。在手术标本中，有21例CPAM、11例肺叶内隔离症、5例先天性肺叶气肿和17例支气管囊肿。所有这些畸形均参照发育障碍/畸形的最新分类进行了描述。
