评估手动针刺对健康个体和中风后患者肱二头肌肌肉功能的即时影响：一项平行组随机临床试验的研究方案。

Evaluation of the immediate effects of manual acupuncture on brachial bicep muscle function in healthy individuals and post stroke patients: a study protocol of a parallel-group randomized clinical trial.

作者信息

Fragoso Ana Paula de Sousa, Ferreira Arthur de Sá

机构信息

Laboratory of Human Movement Analysis, Post-graduation Program of Rehabilitation Science, Augusto Motta University Center, Bonsucesso, Rio de Janeiro, Brazil.

出版信息

Zhong Xi Yi Jie He Xue Bao. 2012 Mar;10(3):303-9. doi: 10.3736/jcim20120309.

DOI:10.3736/jcim20120309

PMID:22409920

Abstract

BACKGROUND

Stroke is a morbid entity in Chinese medicine recognized for over 2 000 years with sensory-motor impairments reported by several classical authors. However, the majority of controlled clinical trials of acupuncture in the treatment of post stroke recovery failed to obtain significant long-term results on functional recovery. Moreover, contradictory results have been obtained regarding the immediate effects of acupuncture stimulation on the electrical activity of human skeletal muscles as observed using surface electromyography. These results raise the question of whether acupuncture has any effect on the neuromuscular level. This study aims to evaluate the immediate effects of manual acupoint stimulation on the electrical activity and strength of the biceps brachii of healthy individuals and patients with chronic hypertonic hemiparesis.

METHODS AND DESIGN

The study proposes a single-blinded randomized clinical trial with four parallel groups. Healthy subjects and post stroke patients with chronic spastic hemiparesis will be submitted to a single acupuncture intervention puncturing either Quchi (LI11) or Tianquan (PC2). The immediate effects on muscle function will be assessed by surface electromyography and isometric force of the biceps brachii muscle as the primary outcome. Secondary outcomes comprise the frequency of patterns in each group, as well as the frequency distribution of manifestations.

DISCUSSION

The proposed study design includes some improvements on common methodological issues on clinical trials with an integrative design. This study design is expected to provide new insights on the neuromuscular effects of acupuncture stimulation in healthy subjects and post stroke patients.

TRIAL REGISTRATION

Brazilian Clinical Trials Registry (www.ensaiosclinicos.gov.br) in English and Portuguese in October 2011.

REGISTRATION NUMBER

RBR-5g7xqh.

摘要

背景

中风是一种在中国医学中已被认识超过2000年的病症，几位古典医学家都记载了其感觉运动障碍。然而，大多数针刺治疗中风后恢复的对照临床试验未能在功能恢复方面取得显著的长期效果。此外，关于针刺刺激对人体骨骼肌电活动的即时影响，使用表面肌电图观察时得到了相互矛盾的结果。这些结果引发了针刺是否对神经肌肉水平有任何影响的问题。本研究旨在评估手法穴位刺激对健康个体和慢性高张力性偏瘫患者肱二头肌电活动和力量的即时影响。