Ozmen Süay, Ozmen Omer Afşin
Inegöl Government Hospital, Otorhinolaryngology Clinics, Bursa, Turkey.
Int J Pediatr Otorhinolaryngol. 2012 Jun;76(6):783-6. doi: 10.1016/j.ijporl.2012.02.040. Epub 2012 Mar 10.
To compare the efficacy of nasal antiseptic ointment and silver nitrate cautery in the treatment of children with recurrent epistaxis.
In this prospective and randomized study, a hundred children with recurrent epistaxis were assigned into two groups. In group 1, patients underwent silver nitrate cauterization, in group 2 patients were treated with nasal antiseptic ointment (oxytetracycline hydrochloride-polymyxin B sulfate); and both groups were followed for 3 months. All of the patients were investigated for allergy with skin prick test.
The ages of patients were similar in both groups (group 1: 9.2±2.7; group 2: 8.2±2.2; p=0.069). Thirty-eight percent of the patients in group 1 and 52% of the patients in group 2 had epistaxis in the three months follow-up. The difference between groups was not significant (p=0.159). Thirteen (26%) of the patients in group 1 and 12 (24%) of the patients in group 2 were found to have allergic symptoms and positive prick test. The rate of allergy was similar in both groups (p=0.817).
Nasal antiseptic ointment and silver nitrate cauterization were found to have similar outcomes in the treatment of recurrent epistaxis.
比较鼻用抗菌软膏和硝酸银烧灼法治疗儿童复发性鼻出血的疗效。
在这项前瞻性随机研究中，将100名复发性鼻出血患儿分为两组。第1组患者接受硝酸银烧灼治疗，第2组患者使用鼻用抗菌软膏（盐酸土霉素 - 硫酸多粘菌素B）治疗；两组均随访3个月。所有患者均通过皮肤点刺试验进行过敏调查。
两组患者年龄相似（第1组：9.2±2.7；第2组：8.2±2.2；p = 0.069）。在3个月的随访中，第1组38%的患者和第2组52%的患者出现鼻出血。两组之间的差异不显著（p = 0.159）。第1组13名（26%）患者和第2组12名（24%）患者被发现有过敏症状且点刺试验呈阳性。两组的过敏率相似（p = 0.817）。
发现鼻用抗菌软膏和硝酸银烧灼法在治疗复发性鼻出血方面有相似的效果。
