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阻塞性综合征性呼吸暂停的患病率及危险因素。

Prevalence of and risk factors for obstructive syndrome apnea.

作者信息

Pons Y, Ballivet de Régloix S, Maurin O, Conessa C

机构信息

Hôpital du Val de Grâce, Service d'ORL et de Chirurgie Cervico-Faciale, 74 boulevard de Port Royal, 75230 Paris cedex 05, France.

出版信息

Rev Laryngol Otol Rhinol (Bord). 2011;132(2):89-94.

Abstract

INTRODUCTION

Obstructive Sleep Apnea Syndrome (OSAS) is becoming an important public health problem because of its frequency and adverse health consequences. The objective of this prospective study was to evaluate the prevalence of and risk factors for OSA in a cohort of subjects working for the french Army.

SUBJECTS AND METHODS

This prospective study was carried out on a sample of volunteers working for the French army. The subjects were recruited at their annual work visit between November 2008 and September 2009. Subjects were asked to complete 2 screening questionnaires (Epworth and Berlin) and were given a medical examination. Subjects suspected of having OSAS (based on high questionnaire scores) were monitored by nocturnal ventilatory polygraphy. OSAS was diagnosed if the subject was found to have an apnea/hypopnea index (AHI) greater than or equal to 5.

RESULTS

In this healthy, young and active population (n = 1054), 4.20% of subjects were diagnosed with OSA. Comparing our two groups of subjects (OSA and non-OSA), several statistically significant (p < .05) differences emerged that may be associated with OSA: the individuals with OSA were older by an average of 7 years, they presented with an average BMI greater than 4.5 kg/m2, an average abdominal girth greater than 12.2 cm and an average cervical circumference greater than 2.6 cm. In addition, they consumed more tobacco when they were smokers and were more likely to present with permanent nasal obstruction. They were also more likely to suffer from gastroesophageal reflux and present with skeletal class II. Finally, they presented with a longer average soft palate as determined by the Mallampati scoring system.

CONCLUSION

We found that the major risk factors for OSAS were age, BMI, abdominal girth and cervical circumference (linear correlations determined by bi-variate analysis).

摘要

引言

阻塞性睡眠呼吸暂停综合征(OSAS)因其发病率及对健康的不良影响,正成为一个重要的公共卫生问题。这项前瞻性研究的目的是评估法国军队中一组受试者的OSA患病率及危险因素。

受试者与方法

这项前瞻性研究是在为法国军队工作的志愿者样本中进行的。受试者于2008年11月至2009年9月的年度工作体检时招募。受试者被要求完成两份筛查问卷(爱泼沃斯和柏林问卷)并接受医学检查。疑似患有OSAS的受试者(基于问卷高分)通过夜间通气多导睡眠图进行监测。如果受试者的呼吸暂停/低通气指数(AHI)大于或等于5,则诊断为OSAS。

结果

在这个健康、年轻且活跃的人群(n = 1054)中,4.20%的受试者被诊断为OSA。比较我们的两组受试者(OSA组和非OSA组),出现了几个具有统计学意义(p <.05)的差异,这些差异可能与OSA相关:患有OSA的个体平均年龄大7岁,他们的平均体重指数(BMI)大于4.5 kg/m²,平均腹围大于12.2 cm,平均颈围大于2.6 cm。此外,他们吸烟时吸烟量更多,更易出现持续性鼻塞。他们也更易患胃食管反流且呈现骨骼Ⅱ类。最后,根据马兰帕蒂评分系统,他们的平均软腭更长。

结论

我们发现OSAS的主要危险因素是年龄、BMI、腹围和颈围(通过双变量分析确定的线性相关性)。

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