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[衣原体诱发的反应性关节炎的诊断与治疗]

[Diagnosis and treatment of Chlamydia-induced reactive arthritis].

作者信息

Zarco Montejo Pedro

机构信息

Unidad de Reumatología, Hospital Universitario Fundación Alcorcón, Madrid, España.

出版信息

Reumatol Clin. 2012 Mar;8 Suppl 1:S20-5. doi: 10.1016/j.reuma.2011.11.003. Epub 2012 Mar 14.

Abstract

Urogenital chlamydia infections are the most prevalent of all sexually transmitted diseases although the number of chlamydia-induced reactive arthritis cases are generally below the estimated incidence of the disease. This may be related with the high rate of asymptomatic chlamydial infections and the lack of adequate diagnostic criteria. Polymerase chain reaction (PCR), a new system for detection of Chlamydia, is one of the most useful techniques for the diagnosis of this disease. Biologic therapy produces theoretical doubts regarding its indication and there is little information related with chlamydia induced reactive arthritis treatment efficacy. Although the usefulness of long antibiotic treatment is not clear, the use of combination antibiotics opens new therapeutic strategies for chlamydia induced reactive arthritis.

摘要

泌尿生殖系统衣原体感染是所有性传播疾病中最常见的,尽管衣原体诱发的反应性关节炎病例数量通常低于该疾病的估计发病率。这可能与衣原体无症状感染的高发生率以及缺乏足够的诊断标准有关。聚合酶链反应(PCR)是一种检测衣原体的新系统,是诊断该疾病最有用的技术之一。生物疗法在其适应症方面存在理论上的疑问,并且与衣原体诱发的反应性关节炎治疗效果相关的信息很少。虽然长期抗生素治疗的有效性尚不清楚,但联合使用抗生素为衣原体诱发的反应性关节炎开辟了新的治疗策略。

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