Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
J Stroke Cerebrovasc Dis. 2012 Nov;21(8):915.e7-9. doi: 10.1016/j.jstrokecerebrovasdis.2012.02.003. Epub 2012 Mar 15.
Beneficial effect of recombinant tissue plasminogen activator (rtPA) in cerebral arterial dissection is controversial. We experienced a 45-year-old man with acute ischemic stroke due to middle cerebral artery dissection, who was treated with rtPA. Characteristic vascular findings indicating dissection became evident only in subsequent angiographic examinations. Our case indicates that serial angiographic examinations should be essential after acute thrombolytic therapy, especially in young patients who are at a high risk of cerebral arterial dissection.
重组组织型纤溶酶原激活剂（rtPA）治疗脑动脉夹层的效果存在争议。我们治疗了一位 45 岁的大脑中动脉夹层所致急性缺血性脑卒中患者，使用了 rtPA。只有在后续血管造影检查中才发现了表明夹层的特征性血管表现。我们的病例表明，急性溶栓治疗后应进行连续血管造影检查，尤其是在高风险的年轻患者中。
