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[碳水化合物缺乏转铁蛋白在使用兴奋剂和未使用兴奋剂运动员中的情况]

[Carbohydrate-deficient transferrin in doping and non-doping athletes].

作者信息

Szabó György, Fraenkel Emil, Szabó Gergely, Keller Eva, Bajnóczky István, Jegesy Andrea, Huszár András, Dinya Elek, Lengyel Gabriella, Fehér János

机构信息

Háziorvosi Szolgálat Enese Szabadság u. 18. 9143.

出版信息

Orv Hetil. 2012 Apr 1;153(13):514-7. doi: 10.1556/OH.2012.29337.

Abstract

UNLABELLED

The determination of carbohydrate deficient transferrin (CDT) concentration is primarily used in social security studies as a proof of regular alcohol consumption exceeding the amount of 60 grams per day.

AIMS

The present study was performed to investigate into how carbohydrate deficient transferrin CDT values in serum are affected by the so-called food supplements and chemicals included in doping lists.

METHODS

The investigation was carried out in 15 bodybuilders of two sport clubs and in 10 boxers. All sportsmen were males. In both groups serum carbohydrate deficient transferrin (CDT%), median red blood cell volume and (MCV) gamma-glutamyl-transpeptidase (GGT) values were measured.

RESULTS

The authors found a significant difference between the two groups only in carbohydrate deficient transferrin CDT% that was the CDT% value in bodybuilders was twice as high as in boxers.

CONCLUSION

Not all the details of the specificity of carbohydrate deficient transferrin (CDT) concentration are known, however, the remarkably high sensitivity of the method makes it suitable and probably economically effective as a pre-screening tool in doping tests.

摘要

未标注

碳水化合物缺乏转铁蛋白(CDT)浓度的测定主要用于社会保障研究,作为每日饮酒量超过60克的常规饮酒证据。

目的

本研究旨在调查血清中碳水化合物缺乏转铁蛋白(CDT)值如何受到兴奋剂清单中所谓的食品补充剂和化学品的影响。

方法

对两个体育俱乐部的15名健美运动员和10名拳击手进行了调查。所有运动员均为男性。测量了两组的血清碳水化合物缺乏转铁蛋白(CDT%)、红细胞体积中位数(MCV)和γ-谷氨酰转肽酶(GGT)值。

结果

作者发现两组之间仅在碳水化合物缺乏转铁蛋白(CDT%)方面存在显著差异,即健美运动员的CDT%值是拳击手的两倍。

结论

虽然碳水化合物缺乏转铁蛋白(CDT)浓度特异性的所有细节尚不清楚,但该方法极高的灵敏度使其适合作为兴奋剂检测的预筛查工具,并且可能在经济上是有效的。

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