Pietrini V, Pinna V, Milone F F
Institute of Neurology, University of Parma, Italy.
J Neurol Sci. 1990 Sep;98(2-3):245-50. doi: 10.1016/0022-510x(90)90265-o.
A neuroradiological investigation of the central nervous system (CNS) in a case of Tangier disease presenting as a syringomyelia-like syndrome is reported. No syringomyelinic cavities were found. However, MRI showed cervical spinal cord atrophy and scattered foci of greater density with T2 weighted images in the white matter of the frontal, parietal and occipital lobes. Cerebral and cervical spinal cord involvement in the course of Tangier disease is now shown for the first time. The authors postulate that the MRI detected alterations are related to the underlying illness.
报告了1例表现为脊髓空洞症样综合征的Tangier病患者的中枢神经系统（CNS）神经放射学检查情况。未发现脊髓空洞症样空洞。然而，MRI显示颈髓萎缩，在额叶、顶叶和枕叶白质的T2加权图像上有散在的高密度灶。Tangier病病程中脑和颈髓受累情况首次得到证实。作者推测MRI检测到的改变与潜在疾病有关。
