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痴呆症的诊断在男性和女性之间存在差异,并取决于年龄和痴呆症的严重程度:来自瑞典痴呆症质量登记处 SveDem 的数据。

Dementia diagnosis differs in men and women and depends on age and dementia severity: data from SveDem, the Swedish Dementia Quality Registry.

机构信息

Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

出版信息

Dement Geriatr Cogn Disord. 2012;33(2-3):90-5. doi: 10.1159/000337038. Epub 2012 Mar 16.


DOI:10.1159/000337038
PMID:22433665
Abstract

AIMS: We examine the dementia assessment with focus on age and gender differences. METHODS: Data from the national quality database, Swedish Dementia Registry (SveDem), including 6,937 dementia patients diagnosed during 2007-2009 at memory clinics were used. We have studied the use of investigations for dementia diagnostics such as cognitive tests, blood and cerebrospinal fluid analyses, electroencephalography, radiological examinations and assessments of functions. Severity of cognitive impairment was assessed with the Mini Mental State Examination (MMSE). RESULTS: There was a significant decrease in the number of total tests used in the elderly group (>75 years) when compared with the middle-aged group (65-75 years) and younger patients (<65 years). The oldest group was examined with 4 of 11 possible tests, the middle-aged group had 5/11 tests performed and the youngest age group 6/11 tests. There was also a significant gender difference in the diagnostic workup, however, mostly attributable to age. The number of tests positively correlated with the level of cognition assessed by the MMSE. CONCLUSION: We show here for the first time the impact of age, gender and MMSE score on the dementia diagnostic workup in a large memory clinic patient population in one country.

摘要

目的:我们研究了痴呆症评估,重点关注年龄和性别差异。

方法:使用来自全国质量数据库瑞典痴呆症登记处(SveDem)的数据,包括 2007-2009 年在记忆诊所诊断的 6937 例痴呆症患者。我们研究了用于痴呆症诊断的检查,如认知测试、血液和脑脊液分析、脑电图、影像学检查和功能评估。认知障碍的严重程度采用简易精神状态检查(MMSE)评估。

结果:与中年组(65-75 岁)和年轻患者(<65 岁)相比,老年组(>75 岁)使用的总测试数量显著减少。最年长的组接受了 11 项可能测试中的 4 项,中年组进行了 5/11 项测试,最年轻的年龄组进行了 6/11 项测试。诊断工作中也存在显著的性别差异,但主要归因于年龄。测试数量与 MMSE 评估的认知水平呈正相关。

结论:我们首次在一个国家的大型记忆诊所患者人群中,展示了年龄、性别和 MMSE 评分对痴呆症诊断工作的影响。

相似文献

[1]
Dementia diagnosis differs in men and women and depends on age and dementia severity: data from SveDem, the Swedish Dementia Quality Registry.

Dement Geriatr Cogn Disord. 2012-3-16

[2]
Costs of diagnosing dementia: results from SveDem, the Swedish Dementia Registry.

Int J Geriatr Psychiatry. 2013-2-26

[3]
The Clock Drawing Test for dementia of the Alzheimer's type: A comparison of three scoring methods in a memory disorders clinic.

Int J Geriatr Psychiatry. 1997-6

[4]
The need for a consensus in the use of assessment tools for Alzheimer's disease: the Feasibility Study (assessment tools for dementia in Alzheimer Centres across Europe), a European Alzheimer's Disease Consortium's (EADC) survey.

Int J Geriatr Psychiatry. 2005-8

[5]
Mortality risk after dementia diagnosis by dementia type and underlying factors: a cohort of 15,209 patients based on the Swedish Dementia Registry.

J Alzheimers Dis. 2014

[6]
Comprehensive geriatric assessment in female elderly patients with Alzheimer disease and other types of dementia.

Arch Gerontol Geriatr. 2007

[7]
Early onset Alzheimer's disease is associated with a distinct neuropsychological profile.

J Alzheimers Dis. 2012

[8]
[Dementia--diagnosis and treatment in a geriatric memory clinic].

Ugeskr Laeger. 2006-5-29

[9]
The assessment of changes in cognitive functioning in the elderly: age- and education-specific reliable change indices for the SIDAM.

Dement Geriatr Cogn Disord. 2012-3-9

[10]
[Oldest-old dementia in a Japanese memory clinic].

Brain Nerve. 2009-8

引用本文的文献

[1]
Temporal trends in sex differences in dementia care-results from the Swedish registry for cognitive/dementia disorders, SveDem.

Sci Rep. 2025-5-29

[2]
Immigration and access to dementia diagnostics and treatment: A nationwide study in Sweden.

SSM Popul Health. 2023-12-2

[3]
Preliminary report of Iranian Registry of Alzheimer's disease in Tehran province: A cross-sectional study in Iran.

Health Sci Rep. 2022-11-22

[4]
The Impact of Disease Registries on Advancing Knowledge and Understanding of Dementia Globally.

Front Aging Neurosci. 2022-2-7

[5]
2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework.

Eur J Nucl Med Mol Imaging. 2021-7

[6]
Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study.

J Intern Med. 2021-4

[7]
Using aggregated data from Swedish national quality registries as tools to describe health conditions of older adults with complex needs.

Aging Clin Exp Res. 2021-5

[8]
Basic Diagnostic Work-Up Is More Complete in Rural than in Urban Areas for Patients with Dementia: Results of a Swedish Dementia Registry Study.

J Alzheimers Dis. 2019

[9]
Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry.

J Alzheimers Dis. 2017

[10]
The societal costs of dementia in Sweden 2012 - relevance and methodological challenges in valuing informal care.

Alzheimers Res Ther. 2016-11-18

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