与I/III重组基因型相关的致命性先天性弓形虫病病例。
Case of fatal congenital toxoplasmosis associated with I/III recombinant genotype.
作者信息
Boughattas S, Ben-Abdallah R, Siala E, Souissi O, Maatoug R, Aoun K, Bouratbine A
机构信息
Laboratoire de Recherche 05SP03, Laboratoire de Parasitologie Clinique, Institut Pasteur Tunis, 13 Place Pasteur, BP74, 1002 Tunis Belvédère, Tunisia.
出版信息
Trop Biomed. 2011 Dec;28(3):615-9.
We report a case of fatal congenital toxoplasmosis case in Tunis (North of Tunisia) associated with I/III recombinant genotype. The Toxoplasma gondii strain was isolated from placenta and characterized molecularly by a multilocus typing (3'SAG2, 5'SAG2, SAG3, AK69, APICO, and UPRT1) and a sulfadiazine resistance mutation analysis. The isolate was shown to be a wild drug sensitive I/III recombinant strain.
我们报告了突尼斯（突尼斯北部）一例与I/III重组基因型相关的致命先天性弓形虫病病例。从胎盘中分离出弓形虫菌株，并通过多位点分型（3'SAG2、5'SAG2、SAG3、AK69、APICO和UPRT1）和磺胺嘧啶耐药性突变分析进行分子特征鉴定。该分离株显示为野生型药物敏感的I/III重组菌株。
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