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从串珠到调控珍珠:染色质的结构与动态。

From beads on a string to the pearls of regulation: the structure and dynamics of chromatin.

机构信息

School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, U.K.

出版信息

Biochem Soc Trans. 2012 Apr;40(2):331-4. doi: 10.1042/BST20120011.

Abstract

The assembly of eukaryotic chromatin, and the bearing of its structural organization on the regulation of gene expression, were the central topics of a recent conference organized jointly by the Biochemical Society and Wellcome Trust. A range of talks and poster presentations covered topical aspects of this research field and illuminated recent advances in our understanding of the structure and function of chromatin. The two-day meeting had stimulating presentations complemented with lively discourse and interactions of participants. In the present paper, we summarize the topics presented at the meeting, in particular highlighting subjects that are reviewed in more detail within this issue of Biochemical Society Transactions. The reports bring to life the truly fascinating molecular and structural biology of chromatin.

摘要

真核染色质的组装及其结构组织对基因表达的调控是最近由生化协会和惠康信托联合组织的一次会议的核心议题。一系列的演讲和海报展示涵盖了该研究领域的热门话题,并阐明了我们对染色质结构和功能的理解的最新进展。为期两天的会议有启发性的演讲,并辅以生动的讨论和与会者的互动。在本文件中,我们总结了会议提出的主题,特别是突出了本期《生化协会学报》中更详细审查的主题。这些报告生动地展示了染色质的真正迷人的分子和结构生物学。

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