Hartschuh W, Weihe E, Egner U
Universitäts-Hautklinik, Heidelberg, F.R.G.
Neurosci Lett. 1990 Aug 24;116(3):245-9. doi: 10.1016/0304-3940(90)90081-j.
By ultrastructural immunohistochemistry using the immunogold technique, immunoreactive (ir) Chromogranin A (CGA) was found to be confined to the secretory vesicles of porcine Merkel cells. CGA was present predominantly in the periphery of the electron-dense core and on the clear halo. These findings indicate that CGA is a regular constituent of Merkel cell secretory granules but probably not exclusively responsible for their electron opacity.
通过使用免疫金技术的超微结构免疫组织化学方法，发现免疫反应性（ir）嗜铬粒蛋白A（CGA）局限于猪默克尔细胞的分泌小泡中。CGA主要存在于电子致密核心的周边以及透明晕中。这些发现表明CGA是默克尔细胞分泌颗粒的正常组成成分，但可能并非其电子不透明性的唯一原因。
