Department of Biological Sciences, Rani Durgavati University, Jabalpur, Madhya Pradesh, India.
Mycopathologia. 2012 Aug;174(2):171-6. doi: 10.1007/s11046-012-9532-0. Epub 2012 Mar 23.
Zygomycosis encompasses infections due to two distinct orders of fungi, Mucorales and Entomophthorales. With rare exception, Entomophthorales are restricted to tropical areas. By contrast, mucorales are ubiquitous opportunistic fungi, which play a crucial part in the natural decay process. In human pathology, they may be opportunistic agents and be responsible for rare infection called (Mucormycosis) zygomycosis. We report two cases of zygomycosis from Madhya Pradesh, Central India, one caused by Rhizopus oryzae in a diabetic patient and another caused by Rhizopus microsporus in an apparently healthy patient. The cases were diagnosed by direct microscopy, histopathological examination and culture. Both the patients were successfully treated with liposomal amphotericin B. Rhizopus microsporus is, for the first time reported from Madhya Pradesh, India, causing rhino-maxillary orbital zygomycosis.
接合菌病包括由两个不同真菌目引起的感染，毛霉目和虫霉目。除了极少数例外，虫霉目仅限于热带地区。相比之下，毛霉目是无处不在的机会性真菌，它们在自然腐烂过程中起着至关重要的作用。在人类病理学中，它们可能是机会性病原体，并导致一种罕见的感染，称为（毛霉病）接合菌病。我们报告了来自印度中央邦的两例接合菌病病例，一例由糖尿病患者中的根霉引起，另一例由 apparently 健康患者中的微小根霉引起。这些病例通过直接显微镜检查、组织病理学检查和培养进行诊断。两名患者均成功接受了脂质体两性霉素 B 治疗。微小根霉首次从印度中央邦报告，引起鼻上颌眶部接合菌病。
