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对于忙碌的心脏外科医生来说,经胸微创主动脉瓣置换术是否耗时过长?

Is transthoracic minimally invasive aortic valve replacement too time-consuming for the busy cardiac surgeon?

作者信息

Cunningham Mark J, Berberian Christopher E, Starnes Vaughn A

机构信息

From the Department of Cardiothoracic Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA USA.

出版信息

Innovations (Phila). 2011 Jan;6(1):10-4. doi: 10.1097/IMI.0b013e31820bc462.

Abstract

OBJECTIVE

: Transthoracic minimally invasive aortic valve replacement (TMI-AVR) is gaining popularity despite criticism that time from incision to the initiation of cardiopulmonary bypass (exposure time, ET), cardiopulmonary bypass time (CPBT), and cross-clamp time (XCT) is excessive. Database analysis was used to characterize these parameters and their associated learning curves.

METHODS

: From 2004 to 2008, 101 patients underwent TMI-AVR at a single institution. Of them, 54 were men (53%) and 47 were women (47%). Mean age was 70 years (range, 24-90 years). ET includes 6-cm incision, second intercostals anterior thoracotomy, medial transection of the third rib, opening pericardial sac, retracing pericardium with stay sutures, placing aortic arterial, and right arterial venous bypass cannulae. ET, CPBT, XCT, and operating room times were calculated. Logarithmic trend analysis established associated learning curves.

RESULTS

: ET steadily improved over time. ET decreased from an average of 51 minutes for the first 25 patients to 39 minutes for the most recent 25 patients. When surgeon experience reached 10 procedures, the ET trend line began to decline steadily and plateaued by 55 cases. Cross-clamp (55 ± 21 minutes), cardiopulmonary bypass (77 ± 31 minutes), and operating room times (304 ± 67 minutes) all remained constant. There were no early deaths or conversions to sternotomy.

CONCLUSIONS

: ET learning curve for TMI-AVR was reflected after 10 procedures with continued gradual improvement. Reliability of TMI-AVR was observed in the absence of a learning curve for XCT, CPBT, and operating room times. A sternal-sparing transthoracic approach for AVR can be performed safely, with expected operative times equivalent to sternotomy.

摘要

目的

经胸微创主动脉瓣置换术(TMI-AVR)尽管受到批评,称其从切口到开始体外循环的时间(暴露时间,ET)、体外循环时间(CPBT)和主动脉阻断时间(XCT)过长,但仍越来越受欢迎。本研究采用数据库分析来描述这些参数及其相关的学习曲线。

方法

2004年至2008年,101例患者在单一机构接受了TMI-AVR。其中,男性54例(53%),女性47例(47%)。平均年龄为70岁(范围24-90岁)。ET包括6厘米切口、第二肋间前外侧开胸、第三肋骨中段横断、打开心包囊、用留置缝线牵拉心包、放置主动脉动脉和右动脉静脉旁路插管。计算ET、CPBT、XCT和手术时间。对数趋势分析确定相关的学习曲线。

结果

ET随时间稳步改善。ET从最初25例患者的平均51分钟降至最近25例患者的39分钟。当外科医生经验达到10例手术时,ET趋势线开始稳步下降,并在55例手术时趋于平稳。主动脉阻断时间(55±21分钟)、体外循环时间(77±31分钟)和手术时间(304±67分钟)均保持不变。无早期死亡或转为胸骨切开术。

结论

TMI-AVR的ET学习曲线在10例手术后得到体现,并持续逐渐改善。在XCT、CPBT和手术时间不存在学习曲线的情况下,观察到TMI-AVR的可靠性。保留胸骨的经胸主动脉瓣置换术可以安全进行,预期手术时间与胸骨切开术相当。

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