Department of Neurosurgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea.
Neurosurg Clin N Am. 2012 Apr;23(2):199-206, vii. doi: 10.1016/j.nec.2012.01.010. Epub 2012 Feb 21.
The insula is a functionally and anatomically complex cortical structure that can be affected by both low-grade and high-grade gliomas. This complexity often prevents many neurosurgeons from attempting to surgically manage insular gliomas. This article reviews the anatomic and functional uniqueness of the insula and the surgical outcomes and lessons learned from previously reported surgical series. Successful management of insular gliomas, defined as maximal resection of the tumor without postoperative neurologic morbidity, can be achieved through a sophisticated understanding of the neurovascular structure of the insular region and an intraoperative functional mapping using cortico-subcortical electrical stimulation.
脑岛是一个功能和解剖结构都很复杂的皮质结构，低级和高级别胶质瘤均可累及。这种复杂性常常使许多神经外科医生不愿意尝试手术治疗脑岛胶质瘤。本文综述了脑岛的解剖和功能独特性，以及既往报道的手术系列中的手术结果和经验教训。通过对脑岛区域的神经血管结构的深入了解和皮质-皮质下电刺激的术中功能定位，可以实现脑岛胶质瘤的成功治疗，定义为在不引起术后神经功能障碍的情况下最大限度地切除肿瘤。
