钴(II)配合物-TMTU-锌催化的帕逊-肯德反应。

CoBr2-TMTU-zinc catalysed-Pauson-Khand reaction.

机构信息

Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing, 100871, China.

出版信息

Chem Commun (Camb). 2012 Aug 25;48(66):8183-5. doi: 10.1039/c2cc17971g. Epub 2012 Mar 23.

DOI:10.1039/c2cc17971g

PMID:22441555

Abstract

A cobalt-TMTU complex, derived from the in situ reduction of CoBr(2) with Zn in the presence of TMTU, can catalyze Pauson-Khand reaction at a balloon pressure of CO, which enables the synthesis of structurally diverse cyclopentenones. This catalytic system works efficiently for both intermolecular and intramolecular PK reactions.

摘要

一个钴-TMTU 配合物，通过在 TMTU 存在下用 Zn 原位还原 CoBr(2) 得到，可以在 CO 的气球压力下催化 Pauson-Khand 反应，从而合成结构多样的环戊烯酮。该催化体系对分子间和分子内的 PK 反应都具有高效性。