Kędzierski W, Kapica M
1Department of Animal Biochemistry and Physiology, Faculty of Veterinary Medicine, Agricultural University, Akademicka 12, 20-033 Lublin, Poland.
Animal. 2008 Apr;2(4):582-7. doi: 10.1017/S1751731108001638.
The effect of acute exercise was studied in a group of 42 clinically healthy young Standardbred trotters. These trotters had been divided into four groups according to their age. Their ages were from 1.5 to 3 years. Three jugular venous blood samples were collected via venipuncture from each horse. These samples were collected while (1) at rest, (2) after the end of the exercise and (3) 30 min after the end of the exercise. Exercise showed a significant increase in plasma leptin concentration (3.8 ± 0.31 at rest v. 4.3 ± 0.37 just after exercise and 4.4 ± 0.47 ng/ml after a 30-min rest; ANOVA P < 0.05). The difference between values obtained 30 min after exercise and at rest was significantly greater in 1.5-year-old horses than in those aged 2.5 years (+1.3 ± 0.43 v. +0.1 ± 0.15 ng/ml; ANOVA P < 0.05). The mean plasma leptin concentration was higher in fillies than in colts (4.9 ± 0.47 v. 3.5 ± 0.36 ng/ml; ANOVA P < 0.05). A positive correlation between the plasma concentrations of leptin and triacylglycerides measured just after exercise was detected (r = 0.65). The acute exercise significantly increased the plasma concentration of ghrelin that was measured just after exercise (1255 ± 55.9 v. 1127 ± 54.2 pg/ml; ANOVA P < 0.05). The exercise-induced age-related changes in the plasma ghrelin concentration were significantly lower in 2.5-year-old trotters than in 1.5-year olds. To sum up, the changes in plasma leptin and ghrelin concentrations during bouts of exertion tend to decrease with age and/or training of Standardbred foals.
在一组42匹临床健康的年轻标准赛马中研究了急性运动的影响。这些赛马根据年龄分为四组，年龄在1.5至3岁之间。通过静脉穿刺从每匹马采集三份颈静脉血样。这些样本在以下三个时间点采集：(1) 休息时；(2) 运动结束后；(3) 运动结束后30分钟。运动后血浆瘦素浓度显著升高（休息时为3.8±0.31，运动刚结束时为4.3±0.37，休息30分钟后为4.4±0.47 ng/ml；方差分析P<0.05）。1.5岁的马运动后30分钟与休息时的值之间的差异明显大于2.5岁的马（分别为+1.3±0.43和+0.1±0.15 ng/ml；方差分析P<0.05）。母马的平均血浆瘦素浓度高于公马（分别为4.9±0.47和3.5±0.36 ng/ml；方差分析P<0.05）。检测到运动刚结束时血浆瘦素浓度与甘油三酯浓度呈正相关（r = 0.65）。急性运动显著增加了运动刚结束时测得的血浆胃饥饿素浓度（分别为1255±55.9和1127±54.2 pg/ml；方差分析P<0.05）。运动引起的血浆胃饥饿素浓度的年龄相关变化在2.5岁的赛马中明显低于1.5岁的赛马。总之，标准赛马驹在运动期间血浆瘦素和胃饥饿素浓度的变化往往会随着年龄增长和/或训练而降低。
