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亚急性硬化性全脑炎一例的组织学及超微结构特征(作者译)

[Histological and ultrastructural features of a case of subacute sclerosing panencephalitis (author's transl)].

作者信息

Pellegrini G, Mariani C, Testa D, Allegranza A

出版信息

Riv Patol Nerv Ment. 1977 Nov-Dec;98(6):319-32.

PMID:224443
Abstract

A case of subacute sclerosing panencephalitis is described from a clinical, histopathological and ultrastructural point of view. The most notable morphologic feature is the presence of a great number of nuclear inclusions inside both neurons and oligodendroglial cells. These inclusions are spread to the whole brain and are decreasing in number from the cerebral cortex towards midbrain. The cerebellum is completely spared. The Authors discuss the problems related to the viral origin of the disease, to the diffusion of the virus inside nervous system and to the myelin degeneration in the light of the recent literature.

摘要

从临床、组织病理学和超微结构角度描述了一例亚急性硬化性全脑炎。最显著的形态学特征是神经元和少突胶质细胞内均存在大量核内包涵体。这些包涵体遍布全脑,数量从大脑皮质向中脑逐渐减少。小脑完全未受累。作者根据最近的文献讨论了与该疾病的病毒起源、病毒在神经系统内的扩散以及髓鞘变性相关的问题。

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