Preel J L, Debray C
Sem Hop. 1979;55(1112):535-7.
During the 18th, 19th, and at the beginning of the 20th century, various observations of inflammatory lesions of the colon and small intestine were published, which were different of tuberculosis to which was at that time attributed every chronical small intestinal inflammatory disease. It was only in 1932, that in a very important paper, Crohn, Ginsburg and Oppenheimer defined the terminal ileitis, afterwards called regional enteritis, and finally more simply Crohn's disease. Twenty years later, in 1952, Crohn's disease of the colon, confused until that date with colonic tuberculosis and with ulcerative colitis, was also identified as a separate entity. Since that time, the number of reported cases has tremendously increased through its is impossible to state whether the incidence of the disease has really increased or whether the diagnosis is done earlier and more precisely. Even today, the exacts limits of the disease are difficult to precise, since the causal agent of the disease is unknown, and that no biological test is completely secure. The present work reports 60 observations of chronic colitis, associated or not with small intestinal inflammation.
在18世纪、19世纪以及20世纪初，有关结肠和小肠炎症性病变的各种观察结果被发表，这些病变与当时被认为是所有慢性小肠炎症性疾病病因的结核病不同。直到1932年，在一篇非常重要的论文中，克罗恩、金斯堡和奥本海默定义了末端回肠炎，后来称为局限性肠炎，最后更简单地称为克罗恩病。二十年后，即1952年，此前一直与结肠结核和溃疡性结肠炎相混淆的结肠克罗恩病也被确认为一种独立的疾病。从那时起，报告的病例数量大幅增加，因为很难确定该病的发病率是否真的上升，还是诊断得更早、更准确。即使在今天，该病的确切范围也难以精确界定，因为该病的病原体尚不清楚，而且没有任何生物学检测是完全可靠的。本研究报告了60例慢性结肠炎的观察结果，这些病例伴有或不伴有小肠炎症。
