Department of Anesthesia, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia, Canada.
Laryngoscope. 2012 May;122(5):1057-61. doi: 10.1002/lary.23228. Epub 2012 Mar 23.
OBJECTIVES/HYPOTHESIS: Postoperative pulmonary complications (PPCs) following head and neck surgery are common. Patients undergoing tracheostomy, free tissue transfer reconstruction, and postoperative ventilation in an intensive care unit (ICU) have a high incidence of PPCs. We sought to define the incidence of PPCs in this cohort and to determine what factors PPCs correlate with.
Retrospective cohort study.
Following institutional research ethics board approval, a retrospective review of patients undergoing major head and neck surgery at a Canadian tertiary care center was conducted. The development of PPCs was the outcome of interest. Quality assurance parameters including ICU and hospital lengths of stay, and mortality were also recorded.
There were 105 patients enrolled, of which 47 (44.8%) sustained one or more PPCs. The most frequent PPC was respiratory failure, accounting for 39 of 94 PPCs observed. Hypertension was the only comorbidity that correlated with development of a PPC (P = .031). Those who sustained PPCs were older than those who did not (median age, 65.6 vs. 58.7 years; P = .005). Development of PPCs correlated with longer ICU and hospital stays. There was increased mortality among patients with PPCs compared to those without (12.8% vs. 1.7%, P = .04).
Patients undergoing major head and neck surgery are at high risk of PPCs. Advanced age and hypertension significantly correlated with PPCs. PPCs correlate with prolonged ICU and hospital stays, and increased mortality. Further research is needed to define risk factors, useful investigations, and effective optimization strategies to mitigate PPCs.
目的/假设:头颈部手术后的肺部并发症(PPCs)很常见。行气管切开术、游离组织转移重建术和术后在重症监护病房(ICU)通气的患者 PPCs 发生率较高。我们旨在定义该队列中 PPCs 的发生率,并确定与 PPCs 相关的因素。
回顾性队列研究。
在获得机构研究伦理委员会批准后,对加拿大一家三级护理中心行头颈部大手术的患者进行了回顾性审查。 PPCs 的发展是感兴趣的结果。还记录了质量保证参数,包括 ICU 和住院时间以及死亡率。
共纳入 105 例患者,其中 47 例(44.8%)发生了 1 种或多种 PPCs。最常见的 PPC 是呼吸衰竭,占观察到的 94 例 PPC 中的 39 例。高血压是唯一与 PPC 发生相关的合并症(P =.031)。发生 PPCs 的患者比未发生 PPCs 的患者年龄更大(中位数年龄:65.6 岁比 58.7 岁;P =.005)。 PPCs 的发生与 ICU 和住院时间延长相关。与无 PPCs 的患者相比,有 PPCs 的患者死亡率更高(12.8%比 1.7%;P =.04)。
行头颈部大手术的患者发生 PPCs 的风险较高。高龄和高血压与 PPCs 显著相关。PPCs 与 ICU 和住院时间延长以及死亡率增加相关。需要进一步研究以确定风险因素、有用的检查和有效的优化策略来减轻 PPCs。