Repin E V, Dolgikh V T, Dolgikh T N, Ershov A V, Repina T V
Urologiia. 2011 Nov-Dec(6):50-4.
A total of 57 patients with chronic bacterial prostatitis were divided into two groups. The control group (n = 28) received standard treatment, the study group (n = 29) received treatment including immunomodulator likopid. The tests for IgA, IgM, IgG, compliment components C3, C4, circulating immune complexes were made, immunophenotyping of peripheral blood lymphocytes was performed, chemiluminescence parameters of whole blood and plasma, content of IL-10, TNF-alpha, IL-lbeta in seminal fluid were assessed. The detected abnormalities in parameters of systemic and mucose-associated immunity give ground for inclusion of immunomodulators in combined treatment of patients with chronic bacterial prostatitis.
总共57例慢性细菌性前列腺炎患者被分为两组。对照组（n = 28）接受标准治疗，研究组（n = 29）接受包括免疫调节剂利可膦在内的治疗。进行了IgA、IgM、IgG、补体成分C3、C4、循环免疫复合物的检测，对外周血淋巴细胞进行了免疫表型分析，评估了全血和血浆的化学发光参数、精液中IL-10、TNF-α、IL-1β的含量。全身和黏膜相关免疫参数检测到的异常情况为在慢性细菌性前列腺炎患者的联合治疗中加入免疫调节剂提供了依据。
