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卵泡刺激素和性激素结合球蛋白与绝经后妇女代谢综合征的关系。

Association of follicle-stimulating hormone and sex hormone binding globulin with the metabolic syndrome in postmenopausal women.

机构信息

Department of Laboratory Medicine, Collegium Medicum, Nicholas Copernicus University, Bydgoszcz, Poland.

出版信息

Clin Biochem. 2012 Jun;45(9):703-6. doi: 10.1016/j.clinbiochem.2012.03.011. Epub 2012 Mar 16.

DOI:10.1016/j.clinbiochem.2012.03.011
PMID:22449337
Abstract

OBJECTIVES

We compared the association of follicle-stimulating hormone (FSH) and sex hormone binding globulin (SHBG) with metabolic syndrome (MetS).

DESIGN AND METHODS

We examined 320 postmenopausal women (148 with MetS and 172 without MetS).

RESULTS

FSH was more strongly associated with MetS probability in the logistic regression model compared to SHBG. Receiver operating characteristic (ROC) curves comparison showed greater areas under the curve for FSH than SHBG concentrations.

CONCLUSIONS

FSH exhibited a stronger coherence to MetS than SHBG in postmenopausal women.

摘要

目的

我们比较了卵泡刺激素（FSH）和性激素结合球蛋白（SHBG）与代谢综合征（MetS）的关联。

设计和方法

我们检查了 320 名绝经后妇女（148 名患有 MetS，172 名没有 MetS）。

结果

与 SHBG 相比，在逻辑回归模型中，FSH 与 MetS 概率的相关性更强。接收器操作特征（ROC）曲线比较显示，FSH 的曲线下面积大于 SHBG 浓度。

结论

在绝经后妇女中，FSH 与 MetS 的一致性强于 SHBG。

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