Dana-Farber Cancer Institute, Boston, MA, USA.
J Pediatr Psychol. 2012 Jul;37(6):650-9. doi: 10.1093/jpepsy/jss050. Epub 2012 Mar 26.
Screening for psychological distress is an important tool for improving survivors' access to psychosocial care. The Brief Symptom Inventory-18 (BSI-18) has been widely used to identify psychological distress in cancer survivors, but few studies have reported on its validity. This study evaluated validity of the BSI-18 by comparing it to the Symptom Checklist-90 (SCL-90).
Concordance of cases identified by the BSI-18 and SCL-90 was examined in a sample of 193 adult survivors of childhood cancer.
Receiver operating characteristics analysis showed strong diagnostic utility of the BSI-18 (area under curve = 0.922). However, the standard BSI-18 case-rule demonstrated low sensitivity (45.2%) against the SCL-90. An alternative case-rule showed better results; sensitivity (87.10%), specificity (83.33%).
The BSI-18 is a useful measure for evaluating distress in adult survivors of childhood cancers; however, the standard BSI-18 case-rule has not been validated for this population, and an alternative case rule should be considered.
心理困扰筛查是提高幸存者获得心理社会关怀的重要工具。症状清单-90（SCL-90）已被广泛用于识别癌症幸存者的心理困扰，但很少有研究报告其有效性。本研究通过与症状清单-90（SCL-90）比较来评估 BSI-18 的有效性。
在 193 名成年儿童癌症幸存者的样本中，检查了 BSI-18 和 SCL-90 确定的病例的一致性。
受试者工作特征分析显示 BSI-18 具有很强的诊断效用（曲线下面积=0.922）。然而，BSI-18 的标准病例规则对 SCL-90 的敏感性较低（45.2%）。替代病例规则显示出更好的结果；敏感性（87.10%），特异性（83.33%）。
BSI-18 是评估儿童癌症成年幸存者困扰的有用工具；然而，BSI-18 的标准病例规则尚未在该人群中得到验证，应考虑替代病例规则。
