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[健康婴儿感染明串珠菌属所致脓毒症]

[Sepsis by Leuconostoc spp. in a healthy infant].

作者信息

Martínez-Pajares José D, Díaz-Morales Olga, Acosta-González Federico, Ramos-Díaz Juan C

机构信息

UGC de Pediatría, Hospital General de Antequera, Antequera, Málaga, Spain.

出版信息

Arch Argent Pediatr. 2012 Apr;110(2):e32-4. doi: 10.5546/aap.2012.e32.

Abstract

Leuconostoc genus, belonging to the lactic acid bacteria group, are Gram-positive bacteria intrinsically resistant to vancomycin, broad distributed in nature and widely used in the food industry. Traditionally considered safe for humans, has recently been implicated in various diseases in susceptible individuals, increasingly isolated and with a broad profile of pathogenicity, and it is now classified as an emerging opportunistic pathogen. Children are particularly vulnerable, especially premature babies and those suffering from severe digestive pathology. The way of entry to the human organism has not been studied in depth. The most frequent are the altered intestine and the skin through loss of barrier integrity. Also are described contamination of parenteral and enteral nutrition, especially associated with the use of gastric tubes. Anecdotal cases reported in immunocompetent patients without underlying disease and no use of external devices have occurred in infants, as the case presented here.

摘要

明串珠菌属属于乳酸菌类,是对万古霉素具有内在抗性的革兰氏阳性菌,广泛分布于自然界,在食品工业中广泛应用。传统上认为对人类安全,但最近发现它与易感个体的各种疾病有关,越来越多地被分离出来且具有广泛的致病性,现在被归类为新兴的机会致病菌。儿童尤其易受影响,特别是早产儿和患有严重消化系统疾病的儿童。进入人体的途径尚未深入研究。最常见的是通过屏障完整性丧失经肠道和皮肤感染。也有关于肠外和肠内营养污染的描述,特别是与胃管的使用有关。在没有潜在疾病且未使用外部装置的免疫功能正常的患者中也有婴儿出现过类似病例,如此处呈现的病例。

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