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Do methoxyflurane and enflurane induce hepatic drug-metabolizing enzymes?

作者信息

Marsh J A, Lucas S A, Harrison G G, Ivanetich K M

出版信息

S Afr Med J. 1979 May 26;55(22):871-7.

PMID:224517
Abstract

The effect of acute anaesthetic (1,0 MAC) and chronic subanaesthetic (0,1 MAC) exposure to methoxyflurane and enflurane on the levels of several liver enzymes is reported. Methoxyflurane appears to be an enzyme-inducing agent similar to spironolactone, whereas enflurane does not appear to be an inducing agent for any of the enzymes studied.

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