三次暴露于中度低压缺氧会降低大鼠海马体某些区域中铜锌超氧化物歧化酶的表达。
Threefold exposure to moderate hypobaric hypoxia decreases the expression of Cu,Zn-superoxide dismutase in some regions of rat hippocampus.
作者信息
Stroev S A, Tyul'kova E I, Pelto-Huikko M T, Samoilov M O
机构信息
Laboratory for Regulation of Brain Neuron Functions, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
出版信息
Bull Exp Biol Med. 2011 Jul;151(3):301-4. doi: 10.1007/s10517-011-1314-z.
The effect of moderate hypobaric hypoxia on the expression of a peptide antioxidant Cu,Zn-superoxide dismutase in rat hippocampal neurons was evaluated in an immunocytochemical study. The expression of Cu,Zn-superoxide dismutase decreased significantly in the dorsal hippocampus (CA1 and CA2) and tended to decrease in ventral regions (CA3 and dentate gyrus) by the 24th hour after 3-fold exposure to hypoxia.
在一项免疫细胞化学研究中，评估了中度低压缺氧对大鼠海马神经元中一种肽抗氧化剂铜锌超氧化物歧化酶表达的影响。在3次暴露于缺氧环境后的第24小时，背侧海马体（CA1和CA2）中铜锌超氧化物歧化酶的表达显著下降，腹侧区域（CA3和齿状回）的表达则有下降趋势。
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