Emery Jennifer, Book Nicole M, Novi Joseph M
From the *Department of Obstetrics and Gynecology, Buffalo Clinic, Buffalo, MN; and †Division of Urogynecology and Reconstructive Pelvic Surgery, Riverside Methodist Hospital, Columbus, OH.
Female Pelvic Med Reconstr Surg. 2010 Nov;16(6):349-52. doi: 10.1097/SPV.0b013e3181f5abf5.
: To identify whether an association exists between post-void urinary leakage and/or coital incontinence and the diagnosis of intrinsic sphincter deficiency (ISD) among women with urinary incontinence.
: Ninety women presenting to a tertiary urogynecology office with complaints of urinary incontinence were included in this retrospective chart review. All patients underwent a complete history and physical examination, including direct questioning about the symptoms of post-void leakage and coital incontinence. Multichannel urodynamic testing was evaluated for each patient and ISD was defined by a Valsalva leak point pressure of less than or equal to 60 cm H2O and/or a maximal urethral closure pressure of less than or equal to 20 cm H2O. The prevalence of ISD among those patients with post-void leakage and/or coital incontinence was evaluated.
: The prevalence of ISD among the study population was 64%. Intrinsic sphincter deficiency was diagnosed in 45/62 patients with post-void leakage and in 13/28 patients without post-void leakage (72.6% and 46.4%, respectively, P = 0.0311). Intrinsic sphincter deficiency was present in 21/24 patients with coital incontinence and 37/66 patients without coital incontinence (87.5% and 56.1%, respectively, P = 0.0061). Patients with both symptoms were diagnosed with ISD 90% of the time, while only 41.7% of patients with neither symptom had ISD (P = 0.0014, sensitivity = 64.5%). Patients with either symptom were diagnosed with ISD 72.7% of the time, compared to 41.7% of patients with neither symptom (P = 0.0117, sensitivity = 82.8%). The positive predictive value for coital incontinence alone and ISD was 87.5%, and for both symptoms was 90%.
: The symptoms of post-void leakage and coital incontinence are associated with ISD. The strong positive predictive value of both symptoms with ISD should encourage physicians to include direct questioning about these symptoms during the history taking and treatment planning for women with urinary incontinence.
确定尿失禁女性患者的排尿后漏尿和/或性交失禁与真性括约肌功能不全(ISD)诊断之间是否存在关联。
本回顾性病历审查纳入了90名因尿失禁主诉就诊于三级泌尿妇科门诊的女性。所有患者均接受了完整的病史和体格检查,包括直接询问排尿后漏尿和性交失禁症状。对每位患者进行多通道尿动力学检测,ISD定义为瓦尔萨尔瓦漏尿点压力小于或等于60 cm H2O和/或最大尿道闭合压力小于或等于20 cm H2O。评估排尿后漏尿和/或性交失禁患者中ISD的患病率。
研究人群中ISD的患病率为64%。在62例排尿后漏尿患者中有45例诊断为真性括约肌功能不全,在28例无排尿后漏尿患者中有13例诊断为真性括约肌功能不全(分别为72.6%和46.4%,P = 0.0311)。24例性交失禁患者中有21例存在真性括约肌功能不全,66例无性交失禁患者中有37例存在真性括约肌功能不全(分别为87.5%和56.1%,P = 0.0061)。有两种症状的患者90%的时间被诊断为ISD,而没有任何一种症状的患者只有41.7%被诊断为ISD(P = 0.0014,敏感性 = 64.5%)。有任何一种症状的患者72.7%的时间被诊断为ISD,而没有任何一种症状的患者为41.7%(P = 0.0117,敏感性 = 82.8%)。仅性交失禁与ISD的阳性预测值为87.5%,两种症状均有的阳性预测值为90%。
排尿后漏尿和性交失禁症状与ISD相关。这两种症状对ISD的强阳性预测值应促使医生在对尿失禁女性患者进行病史采集和治疗规划时,直接询问这些症状。