血管紧张素转换酶抑制剂对人体倾斜反应时血浆肾素活性和醛固酮的影响。
Effect of angiotensin-converting enzyme inhibitor on response of plasma renin activity and aldosterone to tilting in man.
机构信息
Department of Medicine, St George's Hospital, London.
出版信息
Br J Clin Pharmacol. 1974 Aug;1(4):313-7. doi: 10.1111/j.1365-2125.1974.tb00259.x.
Abstract
1 The effect of an angiotensin-converting enzyme inhibitor (SQ 20,881; 0.5 mg/kg) on the response to tilting of plasma renin activity (PRA), plasma aldosterone and cortisol was studied in five normal subjects. 2 PRA rose significantly in both the supine and upright positions following administration of SQ 20,881; no significant effect on aldosterone or cortisol was observed.
摘要
在 5 名正常受试者中研究了血管紧张素转换酶抑制剂（SQ 20,881；0.5mg/kg）对倾斜时血浆肾素活性（PRA）、血浆醛固酮和皮质醇反应的影响。
SQ 20,881 给药后，PRA 在仰卧位和直立位均显著升高；未观察到对醛固酮或皮质醇有显著影响。
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