González L, Rodríguez R, Mencía S, Gil-Ruiz M, Sanavia E, López Herce J
Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España.
An Pediatr (Barc). 2012 Oct;77(4):254-60. doi: 10.1016/j.anpedi.2012.01.028. Epub 2012 Mar 26.
To assess the usefulness of intra-abdominal pressure (IAP) measurement, by the intra-vesical method, in order to identify those patients at risk of developing intra-abdominal hypertension, as well as to analyse the factors that affect the IAP, and to determine their influence on the prognosis in critically ill patients.
Prospective observational study in critically ill children in whom the IAP was monitored as soon as signs of intra-abdominal hypertension appeared. The following variables were analysed: age, sex, reason for admission, underlying disease, previous surgeries, blood pressure, heart rate, central venous pressure, urine output, inotropic therapy, sedation, muscle relaxation, mechanical ventilation, renal replacement techniques, extracorporeal membrane oxygenation, and mortality.
A total of 39 patients were studied. At 24hours from initiating the monitoring of IAP, 74.4% showed IAP ≥ 12mmHg, 33.3%>15mmHg, and 15.4%>20mmHg. After 48hours, 59% had intra-abdominal hypertension. There was a correlation between the central venous pressure (CVP) and IAP at 24 and 48hours (r=0.500, P=.001 and r=0.360, P=.040, respectively). There was no correlation with the other parameters. Only 9 patients required urgent decompression and none developed abdominal compartment syndrome.
IAP monitoring can be useful to diagnose and to promptly treat intra-abdominal hypertension, and thus to prevent the abdominal compartment syndrome. Therefore, it should be measured in critically ill children with abdominal pathology.
通过膀胱内测量法评估腹腔内压(IAP)测量在识别有发生腹腔内高压风险患者中的作用,分析影响IAP的因素,并确定其对危重症患者预后的影响。
对危重症儿童进行前瞻性观察研究,一旦出现腹腔内高压迹象即监测IAP。分析以下变量:年龄、性别、入院原因、基础疾病、既往手术史、血压、心率、中心静脉压、尿量、血管活性药物治疗、镇静、肌肉松弛、机械通气、肾脏替代技术、体外膜肺氧合及死亡率。
共研究39例患者。在开始监测IAP 24小时时,74.4%的患者IAP≥12mmHg,33.3%>15mmHg,15.4%>20mmHg。48小时后,59%的患者出现腹腔内高压。在24小时和48小时时,中心静脉压(CVP)与IAP之间存在相关性(分别为r = 0.500,P = 0.001和r = 0.360,P = 0.040)。与其他参数无相关性。仅9例患者需要紧急减压,无一例发生腹腔间隔室综合征。
IAP监测有助于诊断和及时治疗腹腔内高压,从而预防腹腔间隔室综合征。因此,对于有腹部病变的危重症儿童应进行IAP测量。